- recruitingPHASE1
Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of LAI MMV055 Alone and in Combination With MMV371 in Healthy Participants
This study is testing a new medicine, MMV055, for malaria in healthy volunteers. It will check how safe it is, any side effects, and how it moves through the body, both on its own and with another medicine, MMV371. The goal is to see if it could be a future malaria treatment.
United Kingdom - active not recruitingPHASE1
A Phase 1 Study to Assess an Escalating Dose, Multi-prime Vaccination Schedule of R21/Matrix-M™
This study is testing a new malaria vaccine, R21/Matrix-M™, in healthy adults who've never had malaria. We want to see how safe it is and how well their bodies learn to fight off the disease after getting the vaccine, using different dose schedules.
United Kingdom - recruitingPHASE1
A Study to Investigate the Safety of GSK4024484 in Healthy Adult Participants
This study is looking at a new medicine called GSK4024484 for malaria. It's checking how safe it is in healthy adults and how food affects it. This is an early-stage study to learn more about the medicine before it's given to people with malaria.
United Kingdom - active not recruitingPHASE1
A Study to Compare Two Dosing Regimens for a New Malaria Vaccine
This study is testing a new malaria vaccine called RH5.1. We want to see how safe it is and how well it helps the body fight malaria. Two different ways of giving the vaccine are being compared to find the best way.
United Kingdom - recruitingPHASE1
First-in-Human Dose-escalation of GSK4425689A: Safety, Tolerability, and PK in Healthy Adults
This early study looks at a new medicine called GSK4425689A, which might help prevent or treat malaria. We're testing it in healthy adults to see how safe it is, if it causes side effects, and how the body handles it. It's given either into a vein or under the skin.
United Kingdom - active not recruitingPHASE1, PHASE2
A Study to Assess the Safety and Effectiveness of Two Experimental Malaria Vaccines
This study is testing two new vaccines for malaria, RH5.1 and RH5.2-VLP, to see if they are safe and effective. Researchers will give healthy volunteers the vaccines and then expose some to malaria to see if the vaccines protect them. This is a crucial step towards preventing this serious disease.
United Kingdom - active not recruitingEARLY_PHASE1
A Phase Ia Clinical Trial to Assess the Safety and Immunogenicity of the Blood-stage Malaria Candidate Vaccines RH5.1 in Matrix-M and R78C in Matrix-M in Healthy UK Adults
This study is testing new shots for malaria in healthy adults in the UK. Researchers want to see if the shots are safe, help the body fight malaria, and possibly prevent malaria infection. It's an early-stage study to gather important information.
United Kingdom