- not yet recruitingNA
Heart Rate Variability for Practitioner Stimulated Reflection and Decision-making Optimisation
This study looks at how nurses' stress, measured by heart rate (HRV), affects their decisions in intensive care. By giving nurses feedback on their HRV, the research hopes to help them make better, faster decisions and improve patient care, especially for those on breathing machines.
United Kingdom - recruitingNA
Impact of an Early and Extended Rehabilitation Program Combining Individually Tailored Nutrition and Physical Activities on Patient Outcomes After Invasive Mechanical Ventilation and Vasopressor Therapy in the ICU
This study looks at whether a special programme of nutrition and physical activity can help people recover better after being seriously ill and needing a ventilator in intensive care. It compares this programme to the usual care patients receive.
France - recruitingNA
Partial Neuromuscular Blockade in Acute Hypoxemic Respiratory Failure
This study looks at a new way to help seriously ill patients breathe while on a ventilator. It explores using a special medicine (cisatracurium) to relax muscles just enough for safe, gentle breathing, aiming to avoid complications from full muscle relaxation.
Canada - recruiting
Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO Application
This study looks at how UK doctors set breathing machines for patients having chest surgery where only one lung works. It compares current settings with those suggested by a smartphone app to see if they prevent a common breathing problem called acidosis, ensuring patients breathe comfortably and safely.
Canada - not yet recruitingPHASE3
Ketamine Sedation in the ICU (KANINE) RCT
This study looks at adding a drug called ketamine to usual care for very sick patients in intensive care who need help breathing. It aims to see if ketamine is safe and helpful, potentially reducing how long patients need a breathing machine and improving their recovery.
Canada - recruitingNA
Effect of Post-suction Recruitment on Lung Volume in Mechanically Ventilated ICU Patients
This study looks at how to help the lungs of very ill patients in intensive care breathe better. We're testing if giving a little extra air pressure after clearing breathing tubes helps keep lungs open and healthy.
France - not yet recruitingPHASE1, PHASE2
Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congenital Heart Disease Undergoing Surgical Repair
This study looks at how adjusting breathing machines could help children with heart problems after surgery. We're testing a special way to manage lung pressure to see if it makes their hearts and lungs work better.
Germany - recruiting
Influence of Sarcopenia on the Course of the Diseases
This study looks at how muscle weakness, called sarcopenia, affects people with serious illnesses like cancer or liver problems. We're using simple ultrasound scans and blood tests to find better ways to spot sarcopenia early and understand its impact on a patient's health journey.
Germany - recruiting
Effects of AbClo Fascial Approximation Device in Patients With Open Abdomen on Respiratory Mechanics
This study looks at how a device called AbClo, used after tummy surgery, affects patients' breathing. It checks how the device changes lung pressure and air volume, and if adjusting breathing machines helps to manage these changes.
Canada - recruiting
Intelligent Lung Support in the Intensive Care Unit
This study looks at a new AI-powered computer program called IntelliLung. It helps doctors set up breathing machines for very ill patients in intensive care. Researchers want to see how closely doctors' choices match the program's suggestions to help patients breathe better.
Germany · Italy · Poland - not yet recruiting
The Geniohyoid Muscle in Critical Illness
This study looks at how to measure swallowing muscles in critically ill patients using a simple scanner. Many intensive care patients have trouble swallowing after being on a breathing machine, and we want to see if these muscles shrink. Knowing how to measure them accurately is the first step.
United Kingdom