Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) research hub
5 indexed studies · 2 currently recruiting
- active not recruitingPHASE3
A Trial Comparing Docetaxel 75 mg/m2 (3w) Versus Docetaxel 50 mg/m2 (2w) in Combination With Darolutamide + ADT in mHSPC Patients
This study compares two ways of giving a prostate cancer drug, Docetaxel, along with standard treatments Darolutamide and ADT. It aims to find out which schedule causes fewer serious side effects in men with advanced prostate cancer.
Austria · Germany - recruiting
PROCARE - PROstate Cancer Real World Evidence Registry
This study is gathering information on men with prostate cancer that has come back or spread. It looks at how their condition progresses and how treatments work in real life. It aims to help us understand the best ways to manage different stages of prostate cancer.
Germany - ongoing, recruitingTherapeutic confirmatory (Phase III)
(21140 ARANOTE) A randomized, double-blind, placebo-controlled Phase 3 study of darolutamide in addition to androgen deprivation therapy (ADT) versus placebo plus ADT in men with metastatic hormone-sensitive prostate cancer (mHSPC).
This study looks at a new drug, darolutamide, for men with prostate cancer that has spread and still responds to hormone therapy. It compares darolutamide plus standard hormone therapy to a dummy pill plus standard hormone therapy, to see if darolutamide helps patients live longer without their cancer getting worse.
Spain · Latvia · Lithuania - recruitingPHASE1, PHASE2
TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
This study looks at new combinations of medicines for men with prostate cancer that has spread. It checks if combining a new drug, tulmimetostat, with existing treatments like darolutamide or abiraterone is safe and works well. The goal is to find better ways to treat this type of cancer.
United States · Australia · Brazil - active not recruiting
Impact of Apalutamide in Metastatic Hormone Sensitive Prostate Cancer Patients
This study looks at how a medicine called apalutamide works for men with prostate cancer that has spread. It checks if the medicine helps, how it affects daily life, and gathers real-world information beyond strict trials.
United Kingdom