Metastatic or Locally Advanced Unresectable Solid Tumors research hub

Tuvusertib (M1774) in Participants With Metastatic or Locally Advanced Unresectable Solid Tumors (DDRiver Solid Tumors 301)

This early-stage study is testing a new drug called Tuvusertib (M1774), alone or with another drug called niraparib, for people with advanced solid tumours that have spread or can't be removed by surgery. Doctors want to see if it's safe, how the body handles it, and if it shows any early signs of helping.

Study of tuvusertib (M1774) in combination with DNA Damage Response Inhibitors or Immune Checkpoint Inhibitors