Stroke research hub

Telerehabilitation of Balance Clinical and Economic Decision Support System

This study looks at a new way to help people with balance problems caused by stroke, memory issues, inner ear problems, or Long Covid. It uses a virtual coach at home to guide exercises and improve balance and well-being.

Thinking About Memory: How Confident Are You in Your Memory, and Does it Change With Age?

This study explores how older adults think about their own memory abilities. It compares people with and without diagnosed memory problems to understand how confidence in memory changes with age and different memory tasks, which could help with earlier diagnosis of conditions like dementia.

Five Lives MED to Improve Cognitive Function in Mild Cognitive Impairment

This study looks at whether a digital app called Five Lives MED can help improve thinking skills in people with Mild Cognitive Impairment (MCI). Participants will use the app for 12 weeks, and their progress will be compared to a group receiving general health information.

Cortical Disarray Measurement in Mild Cognitive Impairment and Alzheimer's Disease

This study investigates a new imaging technique, Cortical Disarray Measurement (CDM), to improve the early diagnosis of Alzheimer's disease in people with memory problems. It aims to see if CDM can identify early changes and how these relate to memory over two years, helping us better understand and diagnose Alzheimer’s.

Longitudinal Early-onset Alzheimer's Disease Study Protocol

This study looks at how early-onset Alzheimer's disease develops over time. It compares people with this condition to those without it, gathering information on memory, brain scans, and other health markers to better understand the disease.

Optical Neuroimaging and Cognition

This study looks at how brain oxygen and energy use change in people with Alzheimer's, Lewy Body Dementia, and Mild Cognitive Impairment. We're using new, gentle scanning methods to better understand these conditions and find ways to help with diagnosis and monitoring.

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

This study looks for early signs of Alzheimer's disease by examining blood, brain scans, and digital information. It aims to find new ways to spot the disease before it gets worse, especially in people with memory problems or those who are still healthy.

You, Me and Nature Pilot Study

This study looks at how nature activities led by a helper might benefit people with memory problems like dementia. It's a small trial to see if a bigger study should be done. Participants include people with memory issues and their caregivers.

UK Based Remote Brain Health Clinic (BHC) for Patients With Mild Cognitive Impairment (MCI)

This study looks at a new remote clinic helping people with memory problems understand their condition better. It uses advanced tests, including some for brain fluid, to get a clear diagnosis, all done remotely with checks over time.

A PHASE 1B DOSE RANGE FINDING STUDY OF PHENSERINE COMPARED TO DONEPEZIL IN PARTICIPANTS WITH EARLY OR MILD ALZHEIMER’S DISEASE

This study is looking at a new drug called phenserine for people with early or mild Alzheimer's disease. Researchers want to see how different doses of phenserine affect changes in the brain, and compare it to a common Alzheimer's drug called donepezil.

Evaluation of the Effects of a Nutritional Intervention of Ketogenic Medium-chain Triglycerides and B-vitamins on Cognitive Functioning in Older Adults With Mild Cognitive Impairment (COGNIKET-MCI)

This study looks at whether a special nutritional drink, containing fats called ketogenic medium-chain triglycerides and B-vitamins, can help improve thinking and memory in older adults with mild cognitive impairment. Researchers want to see if it makes a difference compared to a dummy drink.

Cognitive Function, Depression, Anxiety, and Quality of Life in Chronic Heart Failure Patients with Iron Deficiency with and without Anaemia: Effects of Intravenous Iron (Ferric Derisomaltose) CogFer-HF Study