Research.Patient.info
Mitochondrial encephalomyopathy research hub
2 indexed studies · 0 currently recruiting
- ongoing, recruitingTherapeutic exploratory (Phase II)
A Multi-Center, Randomized, Single-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral TTI-0102 for Treatment of Patients with Mitochondrial encephalomyopathy, lactic acidosis and strokelike episodes (MELAS).
This study is testing a new medicine, TTI-0102, for people with MELAS. Researchers want to see if it helps improve how well people can move and feel, and if it's safe to take. It's a type of research where some people get the medicine and others get a dummy pill.
France · Netherlands - authorisedTherapeutic exploratory (Phase II)
An open-label extension study evaluating the safety of zagociguat in participants with MELAS who completed TIS6463-203
This study is looking into the long-term safety of a new medicine called zagociguat for people with MELAS, a rare genetic condition. It's for those who have already been in an earlier study of the drug. Researchers will check for any side effects.
Italy · Germany