MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers research hub

Study of HRO761 Alone or in Combination in Cancer Patients With Specific DNA Alterations Called Microsatellite Instability or Mismatch Repair Deficiency.

This study is testing a new drug, HRO761, for cancers that have specific DNA changes called MSI-high or dMMR. It aims to find a safe and effective dose of HRO761, alone or with other cancer medicines, and see how well it treats these cancers.