Myocardial Infarction research hub

Phase 2, Multicenter, Randomized, Parallel, 3-arm, Placebo-controlled Study to Assess Efficacy and Safety of CDR132L in Patients with Reduced Left Ventricular Ejection Fraction (≤ 45%) After Myocardial Infarction (HF-REVERT)

This study looks at a new treatment (CDR132L) for people who have had a heart attack and now have weakened heart pumping. It aims to see if the treatment helps the heart recover and is safe to use. Patients will either get the new treatment or a dummy treatment.

Heart Attack Research Program- Imaging Study

This study looks at people who've had a heart attack but don't have blockages in their main heart arteries. Researchers use special scans to understand why this happens and track their health for up to 10 years.

Cardio-Renal Registry

This study is looking at patients with kidney disease heart problems. It aims to understand why heart issues are common in people with kidney conditions and how best to treat them. We hope to improve care for these patients.

Barts Sex-CAD Database - Sex Hormones and Inflammatory Status in Coronary Artery Disease

This study looks at how hormones and inflammation affect heart artery disease in men and women, especially for women after menopause. Researchers at Barts Heart Centre hope to find better ways to treat heart conditions by understanding these differences.

Barts-MINOCA Registry

This study looks at heart attack patients in the UK who have clear arteries (MINOCA). Researchers are studying their health over time using existing information to learn more about this condition and how best to care for it. No new tests are involved.

Trans-coronary Cooling and Dilution for Cardioprotection During Revascularisation for ST-elevation Myocardial Infarction

This study is looking at a new way to protect the heart during a heart attack. We're testing if gently cooling the heart directly through a small tube, instead of the whole body, can reduce damage. This might make the current treatment even better.

Outcomes of Patients Who Survived Treatment on an Intensive Care Unit for COVID-19 in England and Wales

This study looks at the health of people in England and Wales one year after they left intensive care for COVID-19. Researchers will compare their health to people who were in intensive care for other reasons. The aim is to understand long-term health effects.

Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II

This study is testing a new smartphone device called AliveCor 12-lead ECG. It aims to see if this device can accurately detect heart attacks (STEMI and NSTEMI) in people with chest pain, just as well as the standard ECG machines used in hospitals.

The Next Leap in Cardiac Magnetic Resonance Imaging:Cycling the Field

This study is developing a new, improved MRI scanner to get more detailed pictures of the heart. Researchers want to see if this new technology can spot differences in heart tissue after a heart attack, helping us understand heart health better.

Non-invasive Coronary Thrombus Imaging to Define These Cause of Acute Myocardial Infarction

This study looks into a new scan that can detect blood clots in heart arteries after a heart attack. It aims to help doctors better understand what causes heart attacks and make sure patients get the right treatment.

Development of Novel Physiological CMR Methods in Health and Disease

This study uses special MRI scans to understand how the heart works in healthy people and those with heart conditions. It looks at how the heart responds to small challenges, like a fluid boost, to find better ways to spot and treat heart problems.

Establishing the Incidence of Tako-tsubo Cardiomyopathy in Scotland

This study in Scotland looks at a heart condition called Takotsubo cardiomyopathy, which acts like a heart attack but isn't. Researchers are finding out how many people have it, what causes it, and how they recover, comparing them to people who've had heart attacks and healthy individuals.

Residual Inflammation and Plaque Progression Long-term Evaluation

This study looks at how inflammation in blood vessels after a heart attack might lead to future problems. We use special scans to see inflammation and track changes in blood vessels over time. The goal is to understand how to better prevent future heart issues.

Sodium-glucose cotransporter-2 inhibitors to stABiLizE coronary atherosclerosis pro-gression after acute Myocardial Infarction in women and men with diabetes mellitus

This study looks at how certain diabetes medications, called SGLT2 inhibitors, might affect the build-up of fatty deposits (atherosclerosis) in the heart's arteries after a heart attack. It aims to see if these medicines can slow down or stop this build-up in people with diabetes.

Early Discharge Pathway Registry

This study looks at people who had a heart attack and were discharged early from the hospital after a procedure called PCI. We want to understand their health and recovery better to improve care for future patients.

Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator Implantation

This study looks at whether a small device, called a defibrillator, is still the best way to prevent sudden death in people who have had a heart attack and have a weakened heart. We want to see if modern medicines alone are just as good.

Barts Revascularisation Registry

This study looks at heart disease (myocardial infarction and angina) and how different treatments, like procedures to open blocked arteries, affect patients. It uses existing information from a large heart centre to learn more about these conditions and improve care.

Ticagrelor monotherapy after coronary stenting in patients with acute myocardial infarction - A prospective single-centre, single-arm phase II study