- recruitingTherapeutic use (Phase IV)
Postmarketing Parallel Randomized Clinical Trial to Determine the Efficacy and Safety of Atropine and DIMS Lenses in the Control of Myopia in a Pediatric Population
This study looks at ways to slow down short-sightedness (myopia) in children. Researchers are comparing two treatments: eye drops called atropine and special spectacle lenses called DIMS lenses. The goal is to see how well they work, how safe they are, and which helps protect children's sight best.
Spain - completedPhase II
Low-dose atropine eye drops to reduce progression of short-sightedness (myopia) in children in the United Kingdom
This study is testing whether low-dose atropine eye drops can stop short-sightedness from getting worse in children aged 6 to 12. Glasses help children see clearly, but they do not stop eyes changing. Researchers want to see if daily drops can safely protect children's long-term eyesight.
United Kingdom · England · Northern Ireland - recruitingNot Applicable
Clinical performance and safety of soft contact lenses in children
This study looks at how well special daily contact lenses and glasses work for short-sighted children aged 8-12. It aims to see if these lenses can help slow down the worsening of short-sightedness and reduce future eye problems, comparing them to regular glasses.
United Kingdom · England - completedNot Applicable
Clinical investigation of soft contact lenses in children
This study looks at new soft contact lenses for children aged 8-15 who are short-sighted and already wear contact lenses. Researchers want to see if these special lenses can help slow down the worsening of short-sightedness and reduce future eye problems.
United Kingdom · England - recruitingTherapeutic confirmatory (Phase III)
A Multicenter, Randomized, Double-Masked, Vehicle-Controlled Study to Assess the Safety and Efficacy of SYD-101 Ophthalmic Solution for the Treatment of Myopia in Children
This study is testing a new eye drop called SYD-101 to see if it can slow down the worsening of short-sightedness (myopia) in children. Researchers want to know if it's safe and how well it works compared to a dummy eye drop over two years.
Slovakia · Austria - recruitingPHASE3
Atropine Eyedrops for Myopia Progression in Children and Adolescents (MODERATO STUDY)
This study is testing if special eye drops can slow down 'short-sightedness' (myopia) in children and teenagers. It's looking at whether two different strengths of atropine eye drops are safe and work better than dummy drops over two years.
Albania · Italy · Poland - recruitingNA
MiSight 1 Day Safety Post-Approval Study
This study is checking how safe a special daily contact lens called MiSight 1 Day is for children in the US. It's for children aged 8-12 who are short-sighted, to make sure the lenses are safe for them to wear every day.
United States · Canada - active not recruitingNA
Effect of Diffusion Optics Technology (DOT) Spectacle Lenses on Choroidal Thickness
This study is looking at how special spectacle lenses might affect eye health in children aged 8 to 14. We want to see if these new lenses, called Diffusion Optics Technology (DOT) lenses, change the thickness of a part of the eye called the choroid, which is thought to be important for how eyesight develops.
Canada - not yet recruitingNA
Red Light Childhood Myopia Proof-of-concept
This study looks at whether a special red LED light can help slow down worsening short-sightedness in children. Researchers want to find the best brightness level to use. It's a first step towards potentially helping children keep their eyesight healthy as they grow.
United Kingdom - active not recruitingPHASE2
Low-dose Atropine Eye Drops to Reduce Progression of Myopia in Children in the United Kingdom
This study looks at whether special eye drops can help slow down short-sightedness in children aged 6 to 12. Short-sightedness makes distant objects blurry. The drops contain a substance called atropine, which researchers hope will stop eyes from getting progressively worse. It's happening in various UK locations.
United Kingdom - not yet recruitingNA
Using Contact Lenses and Spectacle Lenses as Myopia Interventions.
This study looks at how using different contact lenses and glasses can help manage short-sightedness (myopia) in young people aged 11-17. It explores whether switching between special contact lenses and glasses might be a good way to slow down how much short-sightedness progresses.
Canada · United Kingdom