- active not recruiting
MYOPROSP - a Prospective Cohort Study in Myositis
This study, MYOPROSP, aims to better understand myositis, a group of rare muscle diseases. We're looking at adults with suspected or confirmed myositis to collect information and samples. This helps us learn more about diagnosing the condition, how it progresses, and how new treatments work.
United Kingdom - enrolling by invitationPHASE3
A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy
This study looks at a new medicine called efgartigimod for people with certain muscle conditions like myositis. It's for adults who were in a previous study, to see if the medicine is safe and helpful over a long time.
United States · Argentina · Austria - active not recruiting
Investigating Genes in Patients With Polymyositis and Dermatomyositis
This study looks into the genes of people with certain muscle conditions like polymyositis and dermatomyositis. By understanding the genetic causes, researchers hope to develop new and better treatments for these conditions in the future. Participants will be asked to provide a blood sample.
United Kingdom - ongoing, recruitingTherapeutic use (Phase IV)
Transfer of prednisolone into human breast milk and plasma of breastfeeding children - A low intervention cohort study with biobanking of breast milk and plasma
This study looks at how much prednisolone medication, taken by breastfeeding mums, passes into their breast milk and then into their baby's blood. We want to understand if babies are exposed to the medicine and how much.
Sweden - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2, Randomized, Double-Blinded, Placebo-Controlled, Multicenter Study to Evaluate the Safety, Tolerability, and Efficacy of Empasiprubart in Adults With Dermatomyositis
This study is testing a new medicine, empasiprubart, for adults with a condition called dermatomyositis. It's looking at how safe the medicine is, if people can tolerate it, and if it helps improve their symptoms. Some people will get the new medicine, and others will get a dummy treatment (placebo).
Greece · Poland · Italy - recruitingPHASE3
A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)]
This study looks at a new medicine for muscle-weakening conditions called dermatomyositis (DM) and polymyositis (PM). It aims to see how well the medicine, called dazukibart, works to help people with these conditions and if it’s safe.
United States · Argentina · Bulgaria - active not recruitingPHASE2, PHASE3
A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.
This study looks at a new drug, efgartigimod PH20 SC, for adults with active idiopathic inflammatory myopathy (IIM), a condition causing muscle weakness and inflammation. It compares the drug to a dummy treatment to see if it helps improve muscle strength and overall well-being.
United States · Argentina · Australia - active not recruitingPHASE2
A Study of Nipocalimab in Participants With Active Idiopathic Inflammatory Myopathies
This study is looking into a new medication called Nipocalimab for people with active inflammatory myopathies, a condition that causes muscle weakness and inflammation. It aims to see if Nipocalimab is safe and helps more than a dummy treatment.
United States · Canada · Czechia