- recruitingTherapeutic exploratory (Phase II)
A Phase 2, Parallel-Group, Dose-Range-Finding Study With Randomized Double-Blind Treatment and Open-Label Periods to Evaluate the Safety and Efficacy of ALKS 2680 in Subjects With Narcolepsy Type 1
This study is testing a new medicine, ALKS 2680, for people with Narcolepsy Type 1. It aims to see how safe the medicine is and how well different doses work to help with symptoms like extreme sleepiness.
Czechia · Italy · France - recruitingPHASE2
A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
This study looks at a new medicine called ORX750 over a long time. It checks if it's safe, if people can take it well, and if it helps adults with narcolepsy (types 1 and 2) or idiopathic hypersomnia to feel less sleepy.
United States · Canada · Italy - recruitingNA
Deciphering the Interactions Between Food Intake, Sleepiness, and Nighttime Sleep Quality in Patients With Type 1 Narcolepsy and Idiopathic Hypersomnia
This study looks at how food, sleepiness, and sleep quality are linked in people with narcolepsy type 1 or idiopathic hypersomnia, and in healthy individuals. It aims to understand why people with narcolepsy often gain weight, by studying their eating habits and sleep patterns.
France - recruitingPHASE2, PHASE3
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
This study is testing a new medicine, TAK-861, for people with narcolepsy type 1. It checks how safe the medicine is and if it helps reduce sleepiness and sudden muscle weakness. Participants have already taken TAK-861 in previous studies.
United States · Australia · Finland - authorisedTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of ALKS 2680 in Adults With Narcolepsy Type 1
This study is testing a new medicine, ALKS 2680, for adults with Narcolepsy Type 1. Researchers want to see if it helps reduce sleepiness and is safe. Some people will get the new medicine, and others will get a dummy medicine (placebo).
Italy · France · Netherlands