Chronic Obstructive Pulmonary Disease research hub
7 indexed studies · 5 currently recruiting
- recruiting
Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure
This study looks at how chronic respiratory failure affects daily life for people in the UK. We want to understand their quality of life and how different treatments help.
United Kingdom - active not recruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy
This study looks at a new medicine called taldefgrobep alfa for young people with Spinal Muscular Atrophy (SMA). It's for those already on other SMA treatments to see if adding this new medicine can further improve muscle strength and movement.
United States · Belgium · Czechia - recruitingPHASE2
Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients
This study is testing a new medicine, SAT-3247, for boys aged 7-9 with Duchenne muscular dystrophy. We want to find the best dose, see if it's safe, and check if it helps. Some boys will get the real medicine, others a dummy medicine.
United States · Australia · Belgium - active not recruitingPHASE3
Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab
This study looks at the long-term safety and effects of a medicine called apitegromab for people with Spinal Muscular Atrophy (SMA) types 2 and 3. It's for those who have already completed earlier studies with this drug.
United States · Belgium · France - recruitingNA
Optimisation of Mechanical Insufflation:Exsufflation
This study looks at how to make devices that help clear mucus from the lungs work better for people with muscle-weakening conditions. We want to find the best settings for these devices to help patients breathe easier and stay healthier.
United Kingdom - not yet recruitingNA
Nebulised Hypertonic Saline to Decrease Respiratory Exacerbations in Neuromuscular Disease or Neurodisability
This study looks at whether breathing in salty water (hypertonic saline) can help people with certain muscle or brain conditions avoid frequent chest infections. Participants will use a nebuliser twice a day for a year to see if this treatment reduces the need for antibiotics.
United Kingdom - recruiting
Can Waveform and Flow Traces From Mechanical Insuflattion:Exsufflation (MI:E) be Used to Identify Laryngeal Responses to MI:E and Thus Optimise Treatment Algorithms?
This study looks at how a 'cough assist' machine works for people with muscle-weakening conditions. Researchers want to see if they can use the machine's readouts to understand how a patient's throat reacts and improve how therapists use the machine.
United Kingdom