- active not recruitingPHASE3
Olaparib Maintenance Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based Chemotherapy.
This study looks at whether Olaparib tablets can help women with advanced ovarian cancer that has a specific genetic change (BRCA mutation) after their initial chemotherapy, aiming to keep the cancer from returning for longer.
United States · Australia · Brazil - authorisedTherapeutic confirmatory (Phase III)
Comparison of neurocognitive outcome in two standard regimen for treatment of low-risk medulloblastoma (COGNITO-MB)
This study compares different standard treatments for a type of childhood brain cancer called medulloblastoma. It looks at how these treatments affect children's thinking and learning abilities, also known as neurocognitive outcome, over time.
France · Denmark · Germany - ongoing, recruitingTherapeutic exploratory (Phase II)
Impact of neoadjuvant immunotherapy in early stage breast cancer before standard therapy (BIS-Program)
This study is looking at new ways to treat early-stage breast cancer before standard surgery. It's for people with specific types of breast cancer (triple-negative or HER2+). Researchers are testing if certain immune-boosting medicines can help the body fight the cancer better, hoping to improve treatment outcomes.
France - active not recruitingPHASE3
A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
This study is for women with advanced ovarian cancer who've had their first treatment. It's testing if two medications, rucaparib and nivolumab, given after initial treatment, can help prevent the cancer from returning or growing. It compares these drugs to dummy treatments.
United States · Australia · Belgium