- recruitingHuman Pharmacology (Phase I)- Other
A Four Way Crossover Thorough QT/QTc Study to Evaluate the Electrocardiographic Effects of Therapeutic and Supratherapeutic Doses of Cytisinicline in Healthy Smokers
This study is looking at how a new medicine, cytisinicline, affects the heart's electrical activity in healthy smokers. It wants to ensure the medicine is safe for your heart before it can be used for nicotine addiction.
Portugal - recruitingHuman Pharmacology (Phase I)- Other
A Phase I, Open-Label Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics of a Single 3 mg Cytisinicline Dose
This early-stage study is looking at how a smoking cessation medicine called cytisinicline is handled by the body in people with kidney problems. We want to understand how kidney function, including dialysis, affects the medicine's levels in the body to ensure it's used safely.
Portugal · Spain - active not recruiting
Factors Sustaining Tobacco Abstinence in Cancer Patients Treated With Radio-chemotherapy or Radiotherapy
This study looks at why some cancer patients stop smoking long-term after treatment for head, neck, or lung cancer. It follows 100 patients to see what helps them stay smoke-free after radiotherapy or chemoradiotherapy, and what might lead them back to smoking.
France