Non-cystic fibrosis bronchiectasis research hub
6 indexed studies · 3 currently recruiting
- authorisedTherapeutic exploratory (Phase II)
A Randomized, Double-blinded, Placebo-controlled, Parallel Group, Phase 2a Study to Assess the Activity, Safety, and Tolerability of SAR445399 in Adult Participants with Non-Cystic Fibrosis Bronchiectasis (NCFB).
This study looks at a new medicine called SAR445399 for adults with non-cystic fibrosis bronchiectasis. Researchers want to see if the treatment helps clear sticky mucus plugs from the lungs, improves airflow, and lowers the risk of chest flare-ups and infections over the course of one year.
Poland · Spain · France - authorisedHuman Pharmacology (Phase I)- Other
A Two-part study to learn the amount of polymyxin E1 in the body over time formed after a single inhaled dose of colistimethate sodium (CMS) in healthy adults (Part 1) and after single inhaled and vein-infused doses of CMS in adults with non‑cystic fibrosis bronchiectasis (NCFB) (Part 2)
This study looks at an antibiotic called colistimethate sodium (CMS). Researchers want to measure how the medicine moves through the body after it is breathed in or given through a vein. The trial includes healthy adults and adults living with a lung condition called non-cystic fibrosis bronchiectasis.
Belgium · Poland · Bulgaria - recruitingHuman Pharmacology (Phase I)- Other
Not applicable
This study is looking for healthy adults and people with a lung condition called bronchiectasis (not cystic fibrosis related). It's an early-stage study to understand how a new treatment works in the body and if it's safe. Taking part could help improve future treatments for this condition.
Belgium - recruitingNA
Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis Bronchiectasis
This study looks at how a device called SIMEOX, used at home, might help people with a lung condition called non-cystic fibrosis bronchiectasis. Researchers want to see if it improves their quality of life and reduces flare-ups over a long time, compared to standard care.
France · Germany · Poland - authorisedTherapeutic exploratory (Phase II)
A Phase 2b, Multicenter, Randomized, Double-blind, Parallel group, Placebo-controlled, Dose Range Finding Study to Evaluate the Efficacy, Safety, and Tolerability of Nebulized CSL787 in Adults (18 to 85 years) with Non-cystic Fibrosis Bronchiectasis
This study is testing a new inhaled medicine (CSL787) for adults aged 18-85 with a lung condition called non-cystic fibrosis bronchiectasis. Researchers want to see if the medicine can reduce flare-ups, improve breathing, and if it's safe to use compared to a dummy treatment.
Spain · Belgium · Germany - recruitingPHASE2
A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis
This study is testing a new medicine, ensifentrine, for people with a lung condition called non-cystic fibrosis bronchiectasis. We want to see if it helps reduce flare-ups, improve breathing, and make people feel better, compared to a dummy medicine.
United States · Italy · Spain