Non-muscle invasive bladder cancer research hub
7 indexed studies · 1 currently recruiting
- ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study of enfortumab vedotin given in the bladder for treatment of patients with non-muscle invasive bladder cancer (NMIBC).
This study is looking at a new treatment called enfortumab vedotin for bladder cancer that hasn't spread into the muscle. The medicine is put directly into the bladder to see if it can help people with this type of cancer.
France · Spain · Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Phase 1 Dose-escalation Study of UGN-301 in Patients With Recurrent Non-muscle Invasive Bladder Cancer (NMIBC)
This study is looking into a new treatment called UGN-301 for people in the UK with non-muscle invasive bladder cancer (NMIBC) that has returned. It's a very early stage study to find a safe dose and see how the treatment works.
Italy · Spain - authorisedPhase III and phase IV (Integrated)
PROSPECTIVE RANDOMISED CLINICAL TRIAL TO EVALUATE THE EARLY RECURRENCE RATE IN NON-MUSCLE INVASIVE BLADDER CANCER BETWEEN THE USE OF CHEMOHYPERTHERMIA (QH) WITH MITOMYCIN-C PRIOR TO TRANSURETHRAL BLADDER RESECTION IN A MAJOR OUTPATIENT SURGERY PROGRAMME AND TREATMENT WITH MITOMYCIN-C IN NORMOTHERMIA POST-RESECTION.
This study looks at treating bladder cancer that hasn't spread to the muscle. It compares two ways of giving medicine into the bladder to stop the cancer coming back: one uses heat with the medicine before surgery, and the other uses the medicine without heat after surgery.
Spain - active not recruitingPHASE3
Assessment of Efficacy and Safety of Durvalumab Plus BCG Compared to the Standard Therapy With BCG in Non-muscle Invasive Bladder Cancer
This study is testing a new combination treatment for a type of bladder cancer that hasn't spread deep into the bladder wall. It's comparing a new drug called Durvalumab with the standard treatment to see if it's more effective and safe.
Australia · Austria · Belgium - recruitingPHASE1, PHASE2
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027)
This study is testing a new medicine, Sacituzumab Tirumotecan, for a type of bladder cancer that hasn't spread into the muscle. Researchers want to find a safe dose and see how well it works when given directly into the bladder.
United States · Canada · France - active not recruitingPHASE3
A Study of Sasanlimab in People With Non-muscle Invasive Bladder Cancer
This study looked at a new medicine called sasanlimab for early-stage bladder cancer that hasn't spread. It compared sasanlimab with or without BCG, a common bladder cancer treatment. The goal was to see how safe and effective sasanlimab is in preventing the cancer from coming back.
United States · Australia · Belgium - ongoing, recruitingTherapeutic exploratory (Phase II)
A Study of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 (N-803) in Patients With Non-Muscle Invasive Bladder Cancer
This study is looking into a new combination treatment for bladder cancer that hasn't spread into the muscle. It combines a standard treatment, BCG, with a new experimental drug called N-803. The aim is to see if this new combination works better at getting rid of the cancer.
Germany