Not applicable (submitted trial is a bioavailability study in healthy subjects) research hub
5 indexed studies · 5 currently recruiting
- recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
An open label, randomized, single dose, two-sequence, two-treatment, four-period, fully replicate, cross-over pharmacokinetic study comparing Alverine citrate/Simeticone 60 mg/300 mg soft capsules to Meteospasmyl 60 mg/300 mg soft capsules in healthy male and female subjects under fed conditions.
This study is comparing two gas and bloating medicines, Alverine citrate/Simeticone and Meteospasmyl. We want to see if they work the same way in healthy adults. It's an early-stage study to check how the body handles these medications after a meal.
Czechia - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
An open label, randomized, two-period, two-sequence, crossover bioavailability study to assess the pharmacokinetic and safety profile of Valacyclovir Oral Suspension compared to European sourced Valtrex® Tablets in normal, healthy subjects under fasting conditions.
This study compares a new liquid form of valacyclovir medicine with the tablet form already available in Europe. We want to see if both forms deliver the medicine to your body in a similar way and if they are equally safe for healthy adults.
Czechia - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
An open label, randomized, crossover, two-period, two-sequence, multiple dose study to assess the relative bioavailability of Rotigotine 4.5 mg (2 mg/24 hrs) transdermal patch (Test Product) compared to Neupro® 2 mg/24 h Transdermal Patch (Reference product) in 48 healthy adult volunteers under fasting conditions.
This study is comparing a new skin patch for Parkinson's disease with an existing one. We want to see if the new patch delivers the medicine, called rotigotine, into the body in a similar way to the current patch. 48 healthy adults will take part.
Czechia - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
An open label, randomized, crossover, two-period, two-sequence, single dose study to assess the relative bioavailability of Rotigotine 4.5 mg (2 mg/24 hrs) transdermal patch (Test Product) compared to Neupro® 2 mg/24 h Transdermal Patch (Reference product) in 48 healthy adult volunteers under fasting conditions.
This study is testing a new skin patch for delivering medicine, comparing it to an existing one. We're checking how much medicine gets into the bodies of healthy adult volunteers from each patch. This helps make sure new medicines work as expected.
Czechia - recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
An open label, randomized, two-period, two-sequence, crossover bioavailability study to assess the pharmacokinetic and safety profile of Valacyclovir Oral Suspension compared to Valtrex® Tablets in normal, healthy subjects under fasting conditions.
This study is looking at a liquid medicine (oral suspension) form of valacyclovir, a drug used to treat certain viral infections. We want to see how well it's absorbed by the body compared to the tablet form, Valtrex®, in healthy people. This helps us understand if both forms work similarly.
Czechia