- recruitingPHASE3
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy
This study is testing a new medicine, Maridebart Cafraglutide, for adults with sleep apnea who use a CPAP machine and are also overweight or have obesity. We want to see if the medicine helps improve their sleep apnea and is safe to use over 52 weeks.
United States · Australia · Brazil - authorisedTherapeutic use (Phase IV)
TheRapeutic StrAtegies for Obstructive SleeP Apnea in Older Adults with OverweigHt or Obesity: A RandomizEd Clinical TriaL (RAPHAEL study)
This study is looking at how a medicine called Wegovy might help older adults with sleep apnea and who are overweight or obese. It wants to see if Wegovy can reduce how many times people stop breathing during sleep over six months.
Spain - recruiting
Patients with Coronary Artery Disease or At High Cardiovascular Risk: Measuring Compliance with Treatment for Obstructive Sleep Apnea Syndrome
This study looks at how well people with heart disease or high heart risk use treatments for sleep apnea. We're comparing two main treatments, CPAP and a mouth device, to see which is easier to stick with and works best for patients.
France - recruiting
Long Term Oral Appliance Therapy Effectiveness for Obstructive Sleep Apnea Syndrome
This study looks at how well a special mouthguard, called an oral appliance, works over a long time for people with a breathing problem called sleep apnea. It also checks if this treatment affects heart health.
Canada - active not recruitingNA
Obstructive Sleep Apnoea and Cardiac Arrhythmias
This study looks at how sleep apnoea affects the heart, specifically checking for irregular heartbeats. We're using a tiny, implanted heart monitor to see if traditional methods miss important heart problems in people with sleep apnoea.
United Kingdom - active not recruitingNA
Impact of Tele-visit on Patients Continous Positive Airway Pressure (CPAP) Follow-up by Home Care Provider
This study looks at whether online video appointments for people using CPAP machines for sleep apnea work as well as usual check-ups. It tries to find out if these online visits can help people stick with their treatment and if they are happy with this new way of checking in.
France - active not recruiting
Systematic Screening for Obstructive Sleep Apnea During Preoperative Consultation Using AI-preoperative Agents
This study looks at how well a new screening method finds a sleep problem called obstructive sleep apnea (OSA) in people aged 50 and over before surgery. Researchers want to see if this screening helps doctors find more people at risk and if it improves health after operations.
France - active not recruiting
Acoustic OSA Prediction During Wakefulness and Monitoring During Sleep
This study looks at how we can use breathing sounds to find out if someone has sleep apnea, both when they're awake and asleep. We want to make diagnosing sleep apnea easier, quicker, and more comfortable for patients than current methods.
Canada - recruitingNA
North West London Pebble Pathway: Automated OSA Diagnosis
This study looks at a new, easier way to diagnose sleep apnoea at home in North West London. It uses a small, wearable device called AcuPebble to see if it can help people get diagnosed quicker and more comfortably than current methods, potentially saving the NHS money.
United Kingdom - active not recruiting
Multi-morbidity Screening in People With Type 2 Diabetes and Pre Diabetes
This study checks for other health issues often linked with Type 2 diabetes and pre-diabetes, like problems with your heart, liver, or sleep. It's testing a new, more thorough health check-up to find these problems earlier.
United Kingdom - active not recruitingNA
Dual-sided Hypoglossal neRvE stimulAtion for the treatMent of Obstructive Sleep Apnea (DREAM)
This study looks at a new device called the Genio™ system. It aims to see how safe and effective it is for adults with a sleep problem called obstructive sleep apnea (OSA). The device works by stimulating a nerve to help keep your airway open while you sleep.
United States · Australia · Belgium - active not recruitingNA
A Post-market Clinical Follow up of the Genio® System for the Treatment of Obstructive Sleep Apnea in Adults
This study looks at how well the Genio® system works for adults with sleep apnea. It checks if the device is safe and helps people breathe better while they sleep over five years, especially if other treatments haven't worked.
Belgium · France · Germany - recruitingNA
Increasing the Use of an Anti-snoring Mouth Guard (Mandibular Advancement Appliance) to Prevent Upper Airway Collapse During Sleep in Patients With Obstructive Sleep Apnoea.
This study looks at how to help people with snoring and breathing problems (Obstructive Sleep Apnoea) use their special mouthguard more often. Researchers are comparing extra support with usual care to see what works best and why some people use their mouthguards more than others.
United Kingdom - recruiting
Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome
This study looks at how a breathing machine called non-invasive ventilation helps children with Down Syndrome who have sleep apnoea. It aims to understand how this treatment affects their well-being, daily behaviour, and what challenges families face when using it.
Ireland · United Kingdom - not yet recruiting
Development of the Drug and Alcohol Respiratory Health Test
This study is creating a simple test to check lung health in adults who use certain substances. Many people with substance use disorder have breathing problems that often go unnoticed. This new test aims to find these issues early so people can get the right help.
United Kingdom - active not recruiting
The Effect of Continuous Positive Airway Therapy on the Blood Pressure in Sleepy vs Non-sleepy Patients With Obstructive Sleep Apnea
This study looks at how treating sleep apnea affects blood pressure. We want to see if the treatment works differently for people who feel very sleepy compared to those who don't. We're using information from past studies to find out more.
United Kingdom - recruiting
EURO-STIM Registry
This study looks at how well the Inspire System works for people with Obstructive Sleep Apnoea (OSA) over time. It collects information from patients using the device during their regular clinic visits to understand its long-term benefits and how people manage with it.
Austria · Belgium · France - ongoing, recruitingTherapeutic exploratory (Phase II)
A double blind, placebo controlled, parallel, study to evaluate the effects of NAL in Obstructive Sleep Apnea Patients.
This study is looking into a new medication called NACYSTELYN for people with sleep apnoea. It wants to see if this medicine can help reduce how many times breathing stops or gets very shallow during sleep, compared to a dummy medicine.
France · Belgium