- recruitingPHASE2
A Study of Brenipatide in Participants With Opioid Use Disorder
This study is testing a new medicine called brenipatide for people with opioid use disorder. It aims to see if brenipatide, when used with buprenorphine, is safe and works better than a dummy medicine (placebo).
United States · Canada · Puerto Rico - ongoing, recruitingTherapeutic use (Phase IV)
A Phase IV Longitudinal Study of SUBLOCADE (SUBUTEX Prolonged Release) Clinical Outcomes in Adults with Opioid Use Disorder (Opioid Dependence)
This study looks at how well SUBLOCADE, a long-acting injection, helps adults with opioid use disorder. It aims to see if people achieve and maintain recovery over 3 years while using this treatment, checking for symptom improvement and other important health outcomes.
Sweden - ongoing, recruitingTherapeutic use (Phase IV)
(ROAR) Reversal of opioid-induced respiratory depression with opioid antagonists - a pharmacokinetic pharmacodynamic modeling study in opioid naïve individuals and chronic opioid users under real-life conditions
This study looks at how medicines called opioid antagonists can reverse breathing problems caused by strong painkillers (opioids). We're testing these medicines in healthy people and those who use opioids, to understand how quickly and effectively they work to help breathing.
Netherlands - authorisedTherapeutic exploratory (Phase II)
Efficacy of Ketamine for the Prevention of Relapse in Patients with Opioid-Use Disorders (OUD)
This study is looking into whether a medicine called ketamine can help people with opioid use disorder (addiction to strong painkillers or drugs like heroin) stay off opioids and reduce their cravings. It's an early-stage study to see how well it works.
Cyprus