- completed
A phase III trial of intensity-modulated proton beam therapy versus intensity-modulated radiotherapy for multi-toxicity reduction in oropharyngeal cancer
This UK clinical trial compares two forms of radiotherapy for throat cancer: standard radiotherapy and proton beam therapy. Researchers want to find out if proton therapy causes fewer long-term side effects, such as speech and swallowing problems, while working just as well to treat the cancer alongside chemotherapy.
United Kingdom · England · Wales - active not recruitingPHASE2
De-Escalation Radiotherapy in Patients With Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma
This study looks at treating a type of throat cancer linked to HPV. We want to see if we can reduce radiation treatment for some patients to lessen side effects, without making the cancer more likely to come back.
Canada - recruiting
Immune Biomarker Study for Head and Neck Cancer
This study looks at how your body's defence system (immune system) reacts to head and neck cancer. Researchers want to find early warning signs in your blood and tumour to help predict how the cancer might behave and improve future treatments.
Germany - active not recruitingPHASE3
CompARE: Escalating Treatment of Intermediate and High-risk Oropharyngeal Cancer (OPC)
The CompARE trial is testing new treatments for a type of throat cancer called oropharyngeal cancer. It compares different ways of using radiotherapy, surgery, and immunotherapy to see if they improve survival and quality of life for adults with more advanced forms of this cancer.
Ireland · United Kingdom - active not recruitingNA
Study Assessing The "Best of" Radiotherapy vs the "Best of" Surgery in Patients With Oropharyngeal Carcinoma
This study compares two main treatments for early throat cancer: surgery through the mouth (Trans Oral Surgery or TOS) and a type of radiation therapy (IMRT). It aims to see which treatment best preserves a person's ability to swallow during the first year after treatment.
Belgium · France · Germany - recruitingNA
Lymphatic Mapping Of Oropharyngeal Cancer
This study is checking a new way to find if throat cancer has spread to lymph glands in the neck. It aims to improve decisions about treatment, potentially preventing unnecessary procedures or missed cancer, by using a special imaging technique during surgery.
United Kingdom