- recruitingNA
Effectiveness of the Journey Total Knee Arthroplasty Versus Two Standard of Care Total Knee Arthroplasty Prostheses
This study compares a newer knee replacement (Journey II) with two common types (Stryker, Zimmer). We want to see if Journey II helps people move their knees better, walk more easily, and have less pain after surgery for arthritis.
Canada - recruitingPHASE3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
This study looks at a new medicine, NNC0487-0111, for people who are overweight and have knee pain from arthritis. It wants to see if this medicine helps with losing weight and reducing pain compared to a dummy medicine.
United States · Australia · Bulgaria - active not recruiting
JOURNEY™ II CR Total Knee System
This study looks at how safe and effective a new knee replacement, called the JOURNEY™ II CR, is for people with knee arthritis needing a new knee. It follows them for up to 10 years after surgery.
United States · Spain · United Kingdom - recruiting
Comparative Study of Navigation-assisted OrthoPilot® Elite and Robotic-assisted MAKO® Total Knee Arthroplasty
This study compares two ways to do knee replacement surgery: robot-assisted and computer-navigated. We want to see if both methods lead to similar good results for people with knee arthritis needing a new knee.
Germany - active not recruitingNA
All Polyethylene Versus Metal Backed Tibial Components in Knee Replacement
This study compares two types of knee replacement parts for people 75 and older with knee arthritis. We want to see if a newer, cheaper part works as well as the standard one over time, checking pain and movement.
United Kingdom - not yet recruitingNA
Feasibility of Good Boost+ for Adults Awaiting Total Knee Replacement
This study looks at a new exercise programme, Good Boost+, for people waiting for knee replacement surgery. It checks if the programme is practical, if people like it, and what effect it has. This helps decide if a bigger study should be done.
United Kingdom - not yet recruitingNA
Manual Arthroplasty Versus VELYS Robotic-Assisted Solution Functional Alignment Arthroplasty for Knee Osteoarthritis
This study compares standard knee replacement surgery with a new robotic-assisted method for knee arthritis. It aims to see if the robotic approach leads to better pain relief, function, and patient satisfaction, and if it's safer and more efficient.
United Kingdom - recruitingPHASE1
FiH Safety and Feasibility Study Assessing Intra-articular Administration of aeGF in Patients With Knee Osteoarthritis
This study is testing a new cell therapy called aeGF for knee osteoarthritis. It's made from gum tissue and aims to reduce pain and help cartilage. This first-in-human trial checks if a single injection into the knee is safe.
United Kingdom