- completedPhase IV
An assessment of the acceptability and practicality of using Janus kinase inhibitors to treat palmoplantar pustulosis
Palmoplantar pustulosis (PPP) causes painful, pus-filled blisters on the hands and feet. This UK trial looks at whether a daily tablet called upadacitinib is an acceptable and practical treatment. Researchers want to see if patients find the medicine and monitoring manageable before planning a larger national clinical trial.
United Kingdom · England - recruitingTherapeutic exploratory (Phase II)
A Phase 2, multicentre open-label study to explore the effects of sonelokimab in patients with moderate-to-severe pustulosis palmoplantaris
This study is looking at a new medicine called sonelokimab for people with a skin condition called palmoplantar pustulosis (PPP). It wants to see how well the medicine works to reduce the redness and spots on hands and feet after 16 weeks.
Germany - recruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis
This study is looking at a new medicine called bimekizumab for a skin condition called palmoplantar pustulosis (PPP). It wants to see if this medicine works and is safe compared to a dummy treatment.
United States · Canada · China - recruitingPHASE2
A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis
This study is testing a new cream called delgocitinib for adults with palmoplantar pustulosis (PPP), a skin condition causing pus-filled spots on hands and feet. Researchers want to see if the cream is safe and helps improve PPP over 16 weeks.
United States · Canada · Germany