patients with chronic respiratory insufficiency due to amyotrophic lateral sclerosis. research hub

Sustained-release oral morphine to alleviate persistent dyspnea in patients with chronic respiratory insufficiency due to amyotrophic lateral sclerosis outside the administration of ventilatory assistance: prospective multicenter randomized, placebo-controlled study, parallel arms. (OPIDYS-ALS).

This study looks into whether a slow-release morphine tablet can help people with ALS who have breathing difficulties but aren't on breathing support. It aims to see if morphine can make breathing feel more comfortable and improve quality of life.