Phase I study in healthy male volunteers. Intended indication: prophylaxis of transplant rejection in liver research hub

Crossover study to investigate the safety and tolerability as well as the blood levels after three single doses of Tacrolimus, of which 2 are administered via the cheek mucosa and 1 dose via the mouth (oral).

This study is looking at a new way to give a medicine called Tacrolimus. We want to see how safe it is and how much of it gets into the blood when given through the cheek or swallowed. This is an early study in healthy men.