Chronic Respiratory Conditions research hub
7 indexed studies · 5 currently recruiting
- not yet recruiting
The AcCREDiT 2 Study
The AcCREDiT 2 study looks at how to quickly identify infections in people with breathing problems, like pneumonia or flare-ups of conditions like COPD. It aims to improve how we test for these infections and make sure patients get the right treatment faster.
United Kingdom - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Phase 1, open-label, non-comparative, multicenter clinical study to evaluate the safety, tolerability, and pharmacokinetics of ceftolozane/tazobactam (MK-7625A) in pediatric participants with nosocomial pneumonia
This study is looking at a new antibiotic treatment called Zerbaxa for children with a specific type of lung infection they get while in hospital. It aims to see how safe it is, how well children tolerate it, and how the body handles the medicine.
Greece · Spain · Estonia - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
Phase I single-blind clinical trial to evaluate the safety and local immune activation of a toll-like receptor 5 agonist (FLAMOD) administered by aerosol
This early-stage study is looking at a new medicine called FLAMOD for pneumonia. It's given through an inhaler and aims to check if it's safe and how it affects the body's natural defences in the lungs for the first time in people.
France - not yet recruiting
Development of the Drug and Alcohol Respiratory Health Test
This study is creating a simple test to check lung health in adults who use certain substances. Many people with substance use disorder have breathing problems that often go unnoticed. This new test aims to find these issues early so people can get the right help.
United Kingdom - recruitingPHASE3
Randomised Evaluation of COVID-19 Therapy
The RECOVERY trial looks at treatments for serious lung infections like pneumonia, including COVID-19. It helps doctors find the best ways to help hospitalised patients get better and reduce their risk of dying. Many treatments have been tested, and some have been found to be very helpful.
Belgium · Estonia · France - not yet recruiting
Investigating the Impact of Sepsis Phenotypes on Antibiotic Treatment in Patients With Severe Pneumonia and Sepsis
This study looks at how antibiotics work differently in people with severe pneumonia and sepsis. We want to understand if different immune system reactions affect antibiotic levels, aiming to improve treatment and fight antibiotic resistance.
United Kingdom - recruiting
A Study Measuring Markers of Airway Inflammation in Breath Samples From People With Respiratory Diseases and Healthy Volunteers.
This study looks for early signs of lung cancer and other lung problems by testing breath. We're trying to find a simple, quick way to help doctors decide who needs more tests, especially for people with ongoing breathing issues.
United Kingdom