- ongoing, recruitingTherapeutic exploratory (Phase II)
Randomised, open-label and parallel group trial to investigate the effects of oral BI 685509 alone or in combination with empagliflozin on portal hypertension after 8 weeks treatment in patients with clinically significant portal hypertension (CSPH) in compensated cirrhosis
This study looks at new ways to treat high blood pressure in the liver, called portal hypertension, in people with liver scarring (cirrhosis). It tests a new drug, BI 685509, alone or with an existing drug, empagliflozin, to see if they can lower this pressure.
Spain · Austria · Netherlands - active not recruitingPHASE4
Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial.
This study looks at whether a blood pressure medicine called a beta-blocker can prevent bleeding from small swollen veins (varices) in the food pipe for people with liver scarring (cirrhosis). Currently, we only know beta-blockers work for large varices. This research aims to find out if they help with small ones too.
United Kingdom