Primary Hyperoxaluria Type 1 (PH1) research hub
3 indexed studies · 1 currently recruiting
- active not recruitingPHASE3
Long Term Extension Study in Patients With Primary Hyperoxaluria
This study offers long-term treatment with DCR-PHXC for people, including children, with Primary Hyperoxaluria (PH). It checks if the treatment is safe and works well over time for this rare genetic kidney condition.
United States · Australia · Canada - recruitingPHASE1, PHASE2
Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)
This study is testing a new medicine, ABO-101, for people with a rare kidney condition called Primary Hyperoxaluria Type 1 (PH1). It looks at how safe the medicine is, how well the body handles it, and if it could help. It involves both adults and children.
United States · France · Germany - ongoing, recruitingTherapeutic confirmatory (Phase III)
ILLUMINATE-C: A Single Arm Study to Evaluate Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Lumasiran in Patients with Advanced Primary Hyperoxaluria Type 1 (PH1)
This study, called ILLUMINATE-C, is looking at a new medicine called Oxlumo for people with a serious kidney and liver condition called Primary Hyperoxaluria Type 1 (PH1). It's a Phase 3 study to check if the medicine is safe and helps to reduce a harmful substance called oxalate in the body.
France · Netherlands · Belgium