- active not recruitingPHASE3
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)
This study is looking into a new medication called povorcitinib for people with prurigo nodularis, a skin condition causing very itchy bumps. It aims to see how well it reduces itching and skin problems, and if it's safe to use.
United States · Australia · Belgium - active not recruitingPHASE3
A Phase 3, Placebo-controlled, Double-blind Study Assessing Rocatinlimab in Prurigo Nodularis
This study is testing a new medicine, rocatinlimab, for adults with prurigo nodularis. It's designed to see if the medicine can reduce itching and improve skin compared to a dummy medicine, to help people with this itchy skin condition.
United States · Argentina · Australia - active not recruitingPHASE3
A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)
This study looks at the long-term safety of a new medicine called Nemolizumab for people with Prurigo Nodularis. It's for those who have already tried Nemolizumab in a previous study for this skin condition.
United States · Austria · Belgium - ongoing, recruitingTherapeutic confirmatory (Phase III)
INCB 18424-319: A phase 3, double-blind, randomised, vehicle-controlled, efficacy and safety study of ruxolitinib cream in participants with Purigo Nodularis. Topical ruxolitinib evaluation in Prurigo Nodularis (TRuE-PN1)
This study is testing a new cream for Prurigo Nodularis, a skin condition causing very itchy bumps. It compares a cream with the active medicine to a plain cream, to see if the new medicine can help reduce itchiness and improve the skin condition over 12 weeks.
Spain · Italy · Belgium - ongoing, recruitingTherapeutic confirmatory (Phase III)
INCB 18424-320: A phase 3, double-blind, randomised, vehicle-controlled, efficacy and safety study of ruxolitinib cream in participants with Prurigo Nodularis. Topical ruxolitinib evaluation in Prurigo Nodularis (TRuE-PN2)
This study is testing a new cream for people with very itchy skin lumps called Prurigo Nodularis. It wants to see if the cream, called ruxolitinib, can reduce itching compared to a cream without any medicine in it. The study aims to find out how well it works and if it's safe.
Austria · Poland · Spain