- recruiting
Cardiopulmonary exercise testing for pulmonary rehabilitation and exercise tailoring for people with pulmonary fibrosis
This study looks at whether specialized exercise bike tests can help healthcare teams design personalized workout plans for people with pulmonary fibrosis. Researchers want to see if tailoring physical activity to each person's heart and lung fitness makes pulmonary rehabilitation safer, more comfortable, and more effective.
United Kingdom · England - recruitingHuman Pharmacology (Phase I)- First administration to humans
Evaluation of safety, side effects and how the inhaled drug CHF10073 is absorbed, modified and removed from the body when administered alone or in combination with itraconazole in male and female healthy adults
This study is testing a new inhaled medicine called CHF10073 in healthy adults. Researchers want to see if it's safe, what side effects it might cause, and how the body handles it. They'll also check what happens when it's taken with another medicine called itraconazole.
Belgium - not yet recruitingPHASE3
Long-term Extension Study to Evaluate Safety and Tolerability of Admilparant in Participants With Pulmonary Fibrosis
This study looks at a medicine called Admilparant for people with pulmonary fibrosis. It's for those who have already been in similar studies and helps us understand its long-term safety and how well people tolerate it over time.
United States · Argentina · Australia - recruitingHuman Pharmacology (Phase I)- First administration to humans
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Safety, Tolerability and Pharmacokinetic Study of Escalating Single and Multiple Doses of GTX-11 in Healthy Subjects
This early-stage study is testing a new medicine called GTX-11 for the first time in healthy people. Researchers want to see if it's safe, how well the body handles it, and how it moves through the body. This is a first step to see if it could eventually help people with lung scarring (pulmonary fibrosis).
Spain - active not recruitingPHASE2
A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
This study is testing a new inhaled medicine (AP01) for people with progressive pulmonary fibrosis. It aims to see if it's safe and effective, compared to a dummy medicine, over one year, alongside usual care.
United States · Argentina · Australia - recruitingNA
Routine vs On-demand ECMO for Lung Transplantation
This study looks at the best way to use a heart-lung support machine (ECMO) during lung transplants. We're comparing using it for everyone versus only using it if a patient needs it during the operation for conditions like severe lung disease.
Canada - active not recruiting
Exhaled Breath Analysis Using eNose Technology as a Biomarker for Diagnosis and Disease Progression in Fibrotic ILD
This study uses a special "eNose" to sniff out breath patterns in people with lung scarring (pulmonary fibrosis). It aims to see if the eNose can help diagnose the condition, track its changes, and check how well treatments are working.
Australia · France · Germany - recruitingNA
A Non-pharmacological Cough Control Therapy
This study looks at a drug-free way to help people with certain lung diseases (Interstitial Lung Disease or ILD) who have a cough for more than 8 weeks. It wants to see if this new approach can reduce coughing and improve their daily lives.
Canada - recruiting
European Management Platform for Childhood Interstitial Lung Diseases - chILD-EU Register and Biobank
This European study is creating a shared database and biobank for children with rare lung conditions called chILD. It aims to improve how chILD is diagnosed and treated across Europe, by studying patient information and treatment results to find the best care.
Germany · Turkey (Türkiye) · United Kingdom - active not recruiting
Interstitial Lung Disease Exacerbations Study
This study looks at how Interstitial Lung Disease (ILD) suddenly worsens, known as 'exacerbations'. We're reviewing patient records to understand who gets them, how they're treated, and what works best to help those in the UK with this condition.
United Kingdom