Interstitial Lung Disease research hub
14 indexed studies · 11 currently recruiting
- not yet recruiting
FIBRotic Interstitial Lung Disease With Nocturnal hypOXaemia and EXercise Induced desaTuRAtion
This study looks at how breathing during sleep or exercise affects people with lung fibrosis. We want to see if checking oxygen levels in these situations can help predict how their condition might change over time.
United Kingdom - active not recruiting
Improving Pulmonary Hypertension Screening by Echocardiography
This study looks at a new way to spot a type of high blood pressure in the lungs, called pulmonary hypertension, earlier. It uses a special heart scan to find people who might have this condition, even if current tests don't clearly show it.
United Kingdom - recruiting
Accuracy of Smartwatches in Measuring Oxygen Levels in Patients With Pulmonary Hypertension: A Pilot Study
This study checks how well smartwatches measure oxygen levels in people with pulmonary hypertension. Researchers compare smartwatch readings with hospital equipment and blood tests, at rest, after exercise, and in low oxygen, all during a single hospital visit to see if smartwatches are accurate enough.
United Kingdom - recruiting
Clinical Registry for the Characterization of the 'Pulmonary Vascular Phenotype' in Patients With Chronic Obstructive Pulmonary Disease
This study looks at information from people in the UK with COPD who have had a special heart test. It aims to understand how COPD affects the blood vessels in the lungs, especially when people also have high blood pressure in their lungs, called pulmonary hypertension.
Austria · Switzerland · United Kingdom - not yet recruiting
Pulmonary Arterial Hypertension and Associated Cardiovascular Disease Detection Using Artificial Intelligence
This study uses a special AI stethoscope to check for heart conditions like pulmonary hypertension during routine heart scans. By collecting new sound and electrical signals from the heart, researchers hope to make AI better at spotting these conditions early.
United Kingdom - enrolling by invitationPHASE3
A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension
This study looks at the long-term effects and safety of a drug called Ralinepag for people with a lung condition called pulmonary arterial hypertension (PAH). It's for those who have already tried Ralinepag in a previous study.
United States · Argentina · Australia - recruitingNA
Interoceptive Intervention for Pulmonary Hypertension
This study looks into a new way to help people with pulmonary hypertension (PH) feel better emotionally. It's called interoceptive intervention, which helps you understand your body's signals. We're testing if an online group program can improve well-being for PH patients.
United Kingdom - recruitingNA
Development of Novel Physiological CMR Methods in Health and Disease
This study uses special MRI scans to understand how the heart works in healthy people and those with heart conditions. It looks at how the heart responds to small challenges, like a fluid boost, to find better ways to spot and treat heart problems.
United Kingdom - recruiting
Feasibility of Novel Clinical Trial Infrastructure, Design and Technology for Early Phase Studies in Patients With Pulmonary Hypertension (FIT-PH)
This study looks at new ways to monitor people with pulmonary hypertension (high blood pressure in the lungs). Researchers will use small pressure sensors and wearable activity trackers to see if these tools can help doctors better understand and manage the condition.
United Kingdom - recruitingPHASE3
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
This study looks at a new inhaled medicine, called TPIP, for people with high blood pressure in the lungs due to scarring (PH-ILD). It wants to see if the medicine helps them walk further over 24 weeks compared to a dummy medicine.
United States · Argentina · Australia - authorisedTherapeutic use (Phase IV)
The effect of Oxygen sUppleTion on vascular resistance and FLOW: the OUTFLOW study
This study, called OUTFLOW, is looking at how pure oxygen affects blood flow and pressure in people with certain heart and lung conditions. It focuses on conditions like high blood pressure in the lungs and problems with tiny blood vessels in the heart. Researchers will measure how much blood the heart pumps after giving oxygen.
Netherlands - active not recruitingPHASE2
Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPD
This study is testing a new inhaled medicine, frespaciguat, for people with lung disease (COPD) and high blood pressure in their lungs (pulmonary hypertension). Researchers want to see if it helps people walk further.
United States · Argentina · Australia - recruiting
Developing the Probability Algorithm for Pulmonary Hypertension Echocardiography
This study looks at new ways to spot a condition called pulmonary hypertension, which is high blood pressure in the lung arteries. It uses heart scans (echocardiograms) and electrical heart readings (ECGs) to see if adding new measurements can help doctors find the condition earlier and more accurately.
United Kingdom - recruitingPHASE2
A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489
This study looks at a medicine called PF-07868489 for people with high blood pressure in their lungs (Pulmonary Arterial Hypertension). It's for those who have already tried this medicine in an earlier study, to see if it's safe and helps them over a longer time.
United States · Australia · Belgium