- ongoing, recruitingTherapeutic confirmatory (Phase III)
A randomized controlled trial to compare the immunogenicity and skin imprinting of intradermal and intramuscular rabies vaccination < RABISKIMM >
This study compares two ways of giving the rabies vaccine – into the skin or into the muscle. We want to see which method is better at training your body's immune system to fight off the rabies virus, especially looking at how the immune cells remember the vaccine.
Belgium - ongoing, recruitingTherapeutic confirmatory (Phase III)
A two-centre open-label non-inferiority trial to assess the immunogenicity and safety of an intradermal and an intramuscular single-visit dosing regimen of purified chick-embryo cell-culture rabies vaccine in adults
This study is looking at different ways to give the rabies vaccine to adults. It compares a new, simpler way with the usual method to see if it works just as well at protecting people from rabies and if it's safe.
Belgium - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A Phase I, randomized, double-blind, multi-centre, placebo-controlled, dose-escalation study to evaluate the safety, reactogenicity and immunogenicity of AstriVax’ investigational vaccine for the prevention of yellow fever (AVX70120), and of AstriVax’ investigational vaccine for the prevention of rabies (AVX70481), in healthy adults aged 18 to 40 years.
This study is testing two new vaccines: one for yellow fever and one for rabies. It's the very first time these vaccines are being given to people. Researchers want to check if they are safe and if they create an immune response in healthy adults aged 18 to 40.
Belgium - recruitingPhase I
A clinical trial to assess whether a self-amplifying ribonucleic acid (saRNA) vaccine against Rabies viruses is safe and induces immune responses
This study is testing a new rabies vaccine (RAB-Vac) for the first time in humans. We want to check if it's safe and how your immune system reacts. It will involve healthy adults aged 18-50 and won't test if the vaccine protects against rabies.
United Kingdom · England