- active not recruiting
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F
This study looks at how a specific eye condition, linked to Usher Syndrome 1F and a gene called PCDH15, changes over time. Its goal is to help scientists better measure these changes, which will speed up the development of new treatments for this type of sight loss.
United States · Canada · France - active not recruiting
Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study
This study looks at how a serious eye condition called Geographic Atrophy (GA) develops over time. GA is a type of 'dry' Age-related Macular Degeneration (AMD). Researchers are checking for 'biomarkers' in blood and how they relate to changes in the eye.
United States · United Kingdom - not yet recruitingEARLY_PHASE1
First-in-Human, Dose Escalation Trial of AXV-101 in BBS1-Related Retinal Degeneration
This study is testing a new medicine, AXV-101, for young people (aged 4-17) with a specific genetic eye condition called Bardet-Biedl Syndrome 1 (BBS1). It aims to see if the medicine is safe and helps improve eyesight or slow down vision loss.
United Kingdom