Medullary Thyroid Cancer research hub
6 indexed studies · 4 currently recruiting
- active not recruitingPHASE1, PHASE2
A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors
This study looks at a new medicine called Selpercatinib for children and young people (ages 6 months to 21 years) with certain advanced solid tumours or brain tumours. It's for those whose tumours have a specific genetic change (called RET alteration).
United States · Australia · Canada - recruitingNA
HIFU Ablation of Soft Tissue Sarcoma
This study in Oxford is exploring a new, non-invasive treatment called HIFU for soft tissue sarcoma and desmoid tumours. It uses focused ultrasound to destroy cancer cells and aims to understand its safety and effectiveness, offering a different option for patients.
United Kingdom - recruitingPHASE2, PHASE3
DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations
This study is testing a cancer drug called capmatinib to see if it can help adults with different types of cancer that share a specific genetic change (MET mutation). It's already approved for some lung cancers, and now researchers want to know if it works for other cancers too.
United Kingdom - recruitingPHASE3
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)
This study is looking at a new medicine called AL3818 (anlotinib) for people with advanced alveolar soft part sarcoma (ASPS). It aims to see how safe and effective it is. Currently, it's only for ASPS patients.
United States · China · Italy - recruitingPHASE1
A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours
This study is testing a new drug, AVA6000, for people with advanced solid tumours like breast, ovarian, or salivary gland cancer. It aims to find a safe dose and see how well it works when standard treatments may no longer be effective.
United States · United Kingdom - active not recruitingPHASE1, PHASE2
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS
This study is testing a new injection, IP-001, after a heat treatment called thermal ablation for certain advanced cancers (bowel, lung, soft tissue sarcoma) that haven't responded to previous treatments. It aims to see if it's safe and effective, potentially offering a new treatment option.
United States · France · Germany