- active not recruitingPHASE1
A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers
This study is testing a new medicine, IOA-244, for people with certain advanced cancers, including lymphoma and melanoma. It aims to see if the medicine is safe and if it can help the body's immune system fight cancer, both alone and with other treatments.
Italy · United Kingdom - active not recruitingPHASE1, PHASE2
Nous-209 Genetic Vaccine for the Treatment of Microsatellite Unstable Solid Tumors
This study is testing a new ‘genetic vaccine’ alongside an existing cancer drug (Keytruda®) for adults with certain advanced cancers. It aims to see if the combination is safe, how the body reacts to it, and if it helps shrink tumours.
United States · Belgium · Canada - active not recruitingPHASE1, PHASE2
First-in-Human Study of ICT01 in Patients With Advanced Cancer
This study is testing a new drug called ICT01, sometimes with another drug called pembrolizumab (Keytruda), for people with advanced cancers. It aims to find the right dose and see how well it works and if it's safe. It's for adults with various solid tumours or blood cancers.
United States · Belgium · France - enrolling by invitationPHASE1
A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring
This study helps us understand the long-term safety of new treatments for certain cancers like leukemia and lymphoma. People who have already been in an earlier drug trial for these conditions will continue to be monitored to see how they respond over time.
Belgium · France · Georgia - recruitingPHASE1, PHASE2
A Study of ATTR-01 in Participants With Select Epithelial Solid Tumours
This study is testing a new experimental drug, ATTR-01, for people with certain solid cancers. It uses a modified common cold virus to target cancer cells and help your immune system fight them.
Spain · United Kingdom - recruitingPHASE1, PHASE2
A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors
This study is testing a new medicine, CRB-701, for people with certain advanced solid cancers. It aims to find a safe and effective dose, and see which cancers it can treat. Participants will receive the medicine and have tests to check how it works.
United States · France · Italy