Triple Negative Breast Cancer research hub
6 indexed studies · 2 currently recruiting
- recruitingPHASE1, PHASE2
Modi-1 Moditope in Breast, Head and Neck, Ovarian, or Renal Cancer
This study is testing a new vaccine called Modi-1 Moditope for advanced cancers like breast, head and neck, ovarian, or kidney cancer. It aims to see if it's safe, and if it can help the body fight cancer, alone or with other treatments.
United Kingdom - active not recruitingPHASE3
Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer
This study looks at a new drug, Monalizumab, combined with Cetuximab, for people with head and neck cancer that has come back or spread. It compares this combination to Cetuximab with a dummy drug (placebo) to see if it's safe and effective.
United States · Argentina · Australia - recruitingPHASE1
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
This study is testing a new drug, PF-08046054/SGN-PDL1V, alone and with an existing medicine called pembrolizumab, for various advanced cancers. Researchers want to see how safe it is and if it has any effect on the cancer. It's a very early stage study.
United States · Belgium · Canada - ongoing, recruitingTherapeutic exploratory (Phase II)
PEVOsq: Phase II basket trial evaluating the efficacy of a combination of pembrolizumab and vorinostat in patients with recurrent and/or metastatic squamous cell carcinoma
This study looks at a new combination treatment for certain skin cancers that have returned or spread. It uses a specific drug to see how many patients respond positively to the treatment.
France - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
An open-label, phase I multicenter, clinical trial of NECVAX-NEO1 in addition to anti-PD-1 or anti-PD-L1 monoclonal antibody checkpoint inhibitor monotherapy in patients with solid tumors
This study is testing a new medicine, NECVAX-NEO1, alongside standard cancer treatments (like anti-PD-1 or anti-PD-L1 drugs). It's for people with certain solid tumours like lung cancer or melanoma. This early-stage trial aims to see if the new medicine is safe and how it works in the body.
Lithuania - ongoing, recruitingTherapeutic exploratory (Phase II)
Activity and safety of peptide-based immunotherapy in an umbrella window of opportunity phase II study in patients with squamous cell carcinoma of the head and neck.
This study is looking at new treatments for head and neck cancer. It tests three different approaches using special vaccines (IO103, IO102, or both) to see how safe and effective they are. The aim is to help the body's immune system fight the cancer.
Belgium