Systemic Sclerosis (SSc) research hub
7 indexed studies · 6 currently recruiting
- recruitingPHASE2
A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis
This study is testing a new medicine, efgartigimod, for adults with systemic sclerosis. It aims to see if the medicine helps improve symptoms and if it's safe, compared to a dummy medicine. We're looking for people to join for about 15 months.
United States · Argentina · Belgium - active not recruitingPHASE2
Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)
This study is testing a new medicine, tibulizumab, for an illness called systemic sclerosis (scleroderma). We want to see if it helps improve symptoms over 24 weeks, followed by an additional 28 weeks where everyone gets the study drug.
United States · Argentina · Chile - not yet recruitingPHASE1
Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic Autoimmune Rheumatic Diseases
This study is testing a new cell therapy called CAR-T for severe autoimmune diseases like rheumatoid arthritis and lupus. It's looking to see if the treatment is safe and helpful for adults when other treatments haven't worked, using a new method developed at Gustave Roussy.
France - recruitingPHASE1
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
This study is testing a new medicine called FT819 for serious autoimmune diseases like lupus and vasculitis. It's looking at how safe it is and how well it works to reduce disease activity, especially in those who haven't responded to other treatments.
United States · France · Sweden - recruiting
Rare AutoImmune SElf-management Programme Development
This study aims to develop a support program for people with rare autoimmune diseases like lupus and vasculitis. It asks patients and healthcare teams across the UK what kind of support is needed to help people manage their conditions and improve their quality of life.
United Kingdom - recruiting
DERMATOMICS: Identifying Regulators of Skin Homeostasis
This study, DERMATOMICS, aims to better understand severe skin conditions like scleroderma (Systemic Sclerosis). Researchers will look at skin and blood samples to find new ways to treat these conditions and improve the lives of those affected. It focuses on the causes and ways to improve treatment.
United Kingdom - recruitingPHASE1, PHASE2
Controlling Hyperactive Immunity With Long-lived Lymphocytes
This study tests a new treatment, QEL-005, for severe rheumatoid arthritis and systemic sclerosis. It aims to see if it's safe and helps improve symptoms. QEL-005 uses your own modified white blood cells to calm an overactive immune system.
United Kingdom