- recruiting
Investigating Utility of ctDNA and Tumour Evolution in Advanced Thyroid Cancer
This study aims to understand how advanced thyroid cancer behaves, even after treatment. Researchers will collect blood and tissue samples to look for tiny bits of cancer DNA (ctDNA). This could help us track the disease better and create more personalised treatments in the future.
United Kingdom - recruitingPHASE2
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
This study is testing a new oral medicine, APL-101, for people with advanced cancers. It focuses on lung cancer and other solid tumours where specific genetic changes linked to a protein called MET are found. Researchers want to see how well it works and if it's safe.
United States · Australia · Canada - active not recruiting
Differentiation of Benign From Malignant Thyroid Nodules Using Diffuse Reflectance Spectroscopy
This study is looking at a new way to tell if thyroid lumps are harmless or cancerous. Doctors currently use scans and biopsies, but sometimes it's still unclear. This research uses a special light probe on tissue removed during surgery to see if it can help get a clearer answer, especially in these uncertain cases.
United Kingdom - active not recruitingPHASE2, PHASE3
IoN- Is Ablative Radio-iodine Necessary for Low Risk Differentiated Thyroid Cancer Patients
This study, called IoN, is looking at whether radioactive iodine treatment is always needed for people with a common type of low-risk thyroid cancer. It compares giving the treatment with not giving it, to see if patients do just as well without it.
United Kingdom - recruiting
To Perform a Post-market Study of the Performance of the Idylla ThyroidPrint Assay Using Clinical Samples in Predicting the Nature of Indeterminate Thyroid Nodules (ITNs) Across Multiple Centers.
This study looks at a new lab test, Idylla ThyroidPrint, for thyroid lumps that doctors aren't sure about. It checks how well the test can tell if a lump is harmless or cancer, comparing it to what's found after surgery.
United Kingdom