Inflammatory Bowel Diseases (IBD) research hub
16 indexed studies · 9 currently recruiting
- active not recruiting
Development and Validation of a New Paediatric Inflammatory Bowel Disease NUTrition Risk Score (PIBD-NUTS)
This study aims to find the best way to identify children with inflammatory bowel disease (IBD) who are at risk of malnutrition. We're testing an existing tool called PYMS, and if it's not effective, we'll create a new tool specifically for IBD children.
Austria · Croatia · Germany - active not recruitingPHASE3
A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis
This study looks at how well a medicine called risankizumab works and how safe it is for people with ulcerative colitis. It's for those who have already shown improvement with this medicine in a previous study.
United States · Argentina · Austria - active not recruitingPHASE3
A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)
This study looks at the long-term safety and effectiveness of a medicine called Upadacitinib for people with ulcerative colitis. It's for those who haven't fully responded to previous treatment or have completed an earlier study.
United States · Argentina · Australia - active not recruiting
A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)
This study looks at the long-term effects of a medicine called Humira for adults with a bowel condition called ulcerative colitis. It aims to see how well Humira works and if it's safe over a long time when used as doctors usually prescribe it.
United States · Australia · Austria - recruitingPHASE2
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
This study is looking at a new medicine called LY4268989 for adults with moderate to severe ulcerative colitis (UC). It aims to see if the medicine is safe and helps improve symptoms compared to a dummy pill. It's a pill taken by mouth.
United States · Argentina · Brazil - recruiting
CEDUR - German IBD Registry
The CEDUR registry is collecting information on adults in Germany with Crohn's disease, ulcerative colitis, or indeterminate colitis. It helps doctors understand how these conditions are managed in the real world, looking at treatments, quality of life, and safety to improve care.
Germany - recruitingPHASE2
Safety and Efficacy of OD-07656 and of Subsequent Vedolizumab Therapy in Moderately to Severely Active Ulcerative Colitis
This study is testing a new medicine, OD-07656, for people with moderate to severe ulcerative colitis. It also looks at whether OD-07656 can improve the effects of another medicine called vedolizumab when used afterwards. The main goal is to check how well the medicines work and if they are safe.
Australia · Austria · Canada - recruitingPHASE4
De-escalation of Ustekinumab Therapy in Patients With Crohn's Disease and Ulcerative Colitis
This study looks at whether people with Crohn's disease or ulcerative colitis, who are feeling well on ustekinumab, can reduce their dose without their symptoms returning. Researchers want to see if less frequent injections still keep the disease under control.
Canada - recruitingNA
Assessing Interventions of Diet in IBD
This study looks at how different diets, like intermittent fasting, Mediterranean, and Low FODMAP, affect people with inflammatory bowel disease (IBD). We want to see which diets help symptoms, improve life quality, and are easiest to stick with.
Canada - not yet recruitingPHASE2
Modafinil For Fatigue in IBD: A Feasibility Randomised Controlled Trial
This study looks at whether the drug modafinil can help reduce tiredness in people with Crohn's disease or ulcerative colitis. It compares modafinil to a dummy pill to see if it's safe and practical to run a bigger study in the future.
United Kingdom - recruiting
AI-driven Narrow-band Imaging Score for Disease Assessment and Outcome Prediction in Ulcerative Colitis
This study aims to create a new, simple way to check how active Ulcerative Colitis is using special camera tests (colonoscopies). It will also explore using artificial intelligence to make these checks more accurate and help predict how the disease might progress over time.
Belgium · Germany · Ireland - recruitingPHASE2
Impact Of The Gut Microbiota On Host Cells Energy Metabolism in Health And In Inflammatory Bowel Disease
This study looks at how gut germs affect energy in healthy people and those with Inflammatory Bowel Disease (IBD). We want to understand if changes in these germs contribute to IBD. Healthy people get antibiotics, while IBD patients are tested once. We'll use special fiber to see how gut germs break it down.
France - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase II, Multicenter Induction Study with an Active Treatment Extension to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Patients with Moderate to Severe Ulcerative Colitis
This study is testing a new drug, called Vixarelimab, for adults with moderate to severe ulcerative colitis. It aims to see how well it works to reduce symptoms and improve the gut, as well as checking its safety and how the body handles it.
Belgium · Germany · France - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2, Dose-finding, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Safety and Efficacy of Efavaleukin Alfa Induction Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis
This study is looking at a new medicine called Efavaleukin Alfa for people with moderate to severe Ulcerative Colitis. We want to see if it's safe and helps people feel better and get their condition under control within 12 weeks.
Slovakia · Latvia · Finland - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2 Long-Term Extension (LTE) Study to Evaluate The Safety and Efficacy of Efavaleukin Alfa in Subjects With Moderately to Severely Active Ulcerative Colitis
This study looks at a new medicine called Efavaleukin Alfa for people with moderate to severe ulcerative colitis. It's a long-term study to see how safe and effective the medicine is over a year or two, especially regarding side effects.
Austria · Denmark · Finland - recruitingPHASE4
Stopping PPI Therapy in Inactive IBD
This study looks at whether people with Ulcerative Colitis or Crohn's Disease can safely stop taking a common stomach medicine (PPIs). It helps us understand if a bigger study to check the safety of stopping these medicines is possible.
United Kingdom