- active not recruiting
A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)
This study looks at the long-term effects of a medicine called Humira for adults with a bowel condition called ulcerative colitis. It aims to see how well Humira works and if it's safe over a long time when used as doctors usually prescribe it.
United States · Australia · Austria - not yet recruitingPHASE2
Modafinil For Fatigue in IBD: A Feasibility Randomised Controlled Trial
This study looks at whether the drug modafinil can help reduce tiredness in people with Crohn's disease or ulcerative colitis. It compares modafinil to a dummy pill to see if it's safe and practical to run a bigger study in the future.
United Kingdom - active not recruitingPHASE3
A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)
This study looks at the long-term safety and effectiveness of a medicine called Upadacitinib for people with ulcerative colitis. It's for those who haven't fully responded to previous treatment or have completed an earlier study.
United States · Argentina · Australia - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase II, Multicenter Induction Study with an Active Treatment Extension to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Patients with Moderate to Severe Ulcerative Colitis
This study is testing a new drug, called Vixarelimab, for adults with moderate to severe ulcerative colitis. It aims to see how well it works to reduce symptoms and improve the gut, as well as checking its safety and how the body handles it.
Belgium · Germany · France - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2, Dose-finding, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Safety and Efficacy of Efavaleukin Alfa Induction Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis
This study is looking at a new medicine called Efavaleukin Alfa for people with moderate to severe Ulcerative Colitis. We want to see if it's safe and helps people feel better and get their condition under control within 12 weeks.
Slovakia · Latvia · Finland - ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2 Long-Term Extension (LTE) Study to Evaluate The Safety and Efficacy of Efavaleukin Alfa in Subjects With Moderately to Severely Active Ulcerative Colitis
This study looks at a new medicine called Efavaleukin Alfa for people with moderate to severe ulcerative colitis. It's a long-term study to see how safe and effective the medicine is over a year or two, especially regarding side effects.
Austria · Denmark · Finland - recruiting
Development and Validation of a New Paediatric Inflammatory Bowel Disease NUTrition Risk Score (PIBD-NUTS)
This study aims to find the best way to identify children with inflammatory bowel disease (IBD) who are at risk of malnutrition. We're testing an existing tool called PYMS, and if it's not effective, we'll create a new tool specifically for IBD children.
Austria · Croatia · Germany - authorisedTherapeutic exploratory (Phase II)
Fibroblast markers to tackle fibrosis in immune-mediated inflammatory diseases
This study looks at a new scanning method to find areas of scarring in people with certain long-term inflammatory conditions like Crohn's, ulcerative colitis, and some lung diseases. We want to see how this scan relates to markers in the body and help doctors understand these diseases better.
Netherlands - active not recruitingPHASE3
A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis
This study looks at how well a medicine called risankizumab works and how safe it is for people with ulcerative colitis. It's for those who have already shown improvement with this medicine in a previous study.
United States · Argentina · Austria