Unresectable or Metastatic Melanoma research hub
4 indexed studies · 0 currently recruiting
- active not recruitingPHASE3
Study Comparing Investigational Drug HBI-8000 + Nivolumab vs. Placebo + Nivolumab in Patients With Advanced Melanoma
This study looks at a new drug, HBI-8000, combined with another treatment, nivolumab, for advanced skin cancer (melanoma) that has spread or can't be removed. It compares this combination to nivolumab alone, in adults and some teenagers.
United States · Australia · Austria - ongoing, recruitingPhase I and Phase II (Integrated)- Other
An Open-Label, Multicentre Phase 1b/2a Clinical Trial of BI-1607, an Fc-Engineered Monoclonal Antibody to FcγRIIB (CD32b), in Combination with Ipilimumab and Pembrolizumab in Participants with Unresectable or Metastatic Melanoma
This study is testing new combinations of medicines for advanced melanoma, a type of skin cancer that has spread or can't be removed by surgery. It looks at how safe the medicines are and how well they shrink tumours.
Germany · Spain - ongoing, recruitingTherapeutic exploratory (Phase II)
A Randomized, Open-Label, Multicenter, Phase II Study of Multiple Doses of RO7247669 in Participants with Previously Untreated Unresectable or Metastatic Melanoma
This study is testing a new medicine called RO7247669 for advanced skin cancer (melanoma) that has spread or can't be removed by surgery. It's an early-stage trial looking at how safe the medicine is and if it can help slow down or stop the cancer from growing.
Poland · Greece · Slovakia - ongoing, recruitingTherapeutic exploratory (Phase II)
An open label, single arm trial evaluating the efficacy and safety of EVX-01 in combination with pembrolizumab in checkpoint inhibitor treatment naïve adults with unresectable or metastatic melanoma
This study looks at a new drug, EVX-01, combined with pembrolizumab (Keytruda) for adults with advanced melanoma that can't be removed by surgery. It aims to see how well this combination shrinks tumours and how safe it is.
Italy