- Ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Single Dose Crossover Comparative Bioavailability and Food Effect Study of Celecoxib 10 mg/1 mL Oral Suspension versus Celebrex®️ (celecoxib) 200 mg Capsules Following the Administration of a 200 mg Dose in Healthy Adult Volunteers / Fasting and Fed State.
This study is comparing a new liquid form of celecoxib (for pain relief) with the standard capsule. We want to see how well the body absorbs the liquid version, both with and without food, to make sure it works similarly to the well-known capsule.
For: Musculoskeletal and connective tissue disorders · Dysmenorrhea · Acute painCzechia - Ongoing, recruitingTherapeutic use (Phase IV)
Early ablation of atrial fibrillation in patients with hypertrophic cardiomyopathy
This study looks at treating an irregular heartbeat called atrial fibrillation (AF) early in people with a heart condition called hypertrophic cardiomyopathy (HCM). It's trying to find out if early treatment of AF helps prevent serious health issues like stroke or further heart problems.
For: Hypertrophic cardiomyopathy (HCM) is the most common genetically determined disease of the heart · characterized by a varied picture and clinical course. The first comprehensive clinical description of the disease comes from the 1960s. Currently · the disease is diagnosed on the basis of a phenotypic picture showing left ventricular hypertrophyPoland - Ongoing, recruitingHuman Pharmacology (Phase I)- Other
A PHASE 1, OPENLABEL, SINGLECENTER STUDY TO EVALUATE DRUGDRUG INTERACTIONS WITH GEMFIBROZIL, ITRACONAZOLE, AND CARBAMAZEPINE AND THE FOOD-EFFECT ON ORAL LERIGLITAZONE IN MALE HEALTHY SUBJECTS
This study is looking at how a new drug, leriglitazone, behaves in the body of healthy men. It checks if other common medicines or food affect how leriglitazone works. This helps us understand its safety and effectiveness for conditions like Adrenoleukodystrophy.
For: AdrenoleukodystrophyPoland