- Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Multicenter, Randomized, Double-Blind, Placebo and Active Comparator Controlled Phase 3 Study to Evaluate the Efficacy and Safety of ESK-001 in Patients with Moderate to Severe Plaque Psoriasis (ONWARD1)
This study is testing a new medicine, ESK-001, for people with moderate to severe plaque psoriasis. It compares ESK-001 to a common treatment (Otezla) and a dummy pill (placebo) to see how well it works and if it's safe.
For: Moderate to Severe Plaque PsoriasisBulgaria · Belgium · Portugal - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Multicenter, Randomized, Double-Blind, Placebo and Active Comparator Controlled Phase 3 Study in Patients with Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001 (ONWARD2)
This study is testing a new medicine, ESK-001, for people with moderate to severe plaque psoriasis. Researchers want to see if it's safe and helps clear up skin patches better than a dummy pill or an existing medicine (Otezla).
For: Moderate to Severe Plaque PsoriasisPoland · Germany · Spain - Ongoing, recruitingTherapeutic exploratory (Phase II)
Plethysmography with acetylcholin and carbacholin – A clinical method study
For: Vascular dysfunctionDenmark - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3B, Multi Center, Open-label Long-term Extension Study of Apremilast (CC-10004) in Pediatric Subjects from 6 Through 17 Years of Age with Moderate to Severe Plaque Psoriasis
For: Moderate to Severe Plaque PsoriasisSpain · Czechia · Belgium - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, Multicenter, Double-Blind, Placebo- and Active Comparator-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-279 in Subjects with Moderate-to-Severe Plaque Psoriasis
For: Moderate to Severe Plaque PsoriasisPoland · Italy · Germany - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, Multicenter, Double-Blind, Placebo- and Active Comparator-Controlled Study With a Randomized Withdrawal and Retreatment Period to Evaluate the Efficacy, Safety, and Tolerability of TAK-279 in Subjects With Moderate-to-Severe Plaque Psoriasis
For: Moderate to Severe Plaque PsoriasisGermany · Poland · Latvia