- Ongoing, recruitingTherapeutic use (Phase IV)
InSaKa trial: Insulin dextrose infusion versus nebulized salbutamol versus combination of salbutamol and insulin dextrose in acute hyperkalemia: a randomized clinical trial
This study, called InSaKa, is looking at the best way to treat a condition called hyperkalemia, where there's too much potassium in the blood. It compares different treatments, including insulin and dextrose, a breathing treatment called salbutamol, and a combination of both, to see which works best and is safest.
For: HyperkalemiaFrance - Ongoing, recruitingTherapeutic exploratory (Phase II)
Evaluation of the efficacy of intra venous dornase alfa (Pulmozyme®) on arterial recanalization in post-thrombectomy angiography in patients managed for ischemic stroke with thrombolysis and eligible for thrombectomy: a single-center phase II trial.
This study looks at whether a drug called Pulmozyme, given through a vein, can help clear blood clots in the brain after a stroke. It's for patients who have had a stroke and are having an operation to remove the clot, to see if Pulmozyme helps blood flow return to normal more quickly.
For: Ischemic strokeFrance - AuthorisedTherapeutic confirmatory (Phase III)
Comparison of azathioprine to methotrexate in combination therapy with adalimumab in Crohn’s Disease: an open-label randomized controlled trial
This study looks at how well two different medicines, azathioprine and methotrexate, work when given with another medicine called adalimumab. It’s for adults with Crohn’s disease and aims to see which combination helps heal the gut lining better.
For: Crohn’s DiseaseFrance - Ongoing, recruitingTherapeutic exploratory (Phase II)
CONCOMITANT ADMINISTRATION OF LICENSED VACCINES AGAINST COVID-19 AND FLU WITH OR WITHOUT MF59 ADJUVANT: A MULTI-CENTRE, RANDOMIZED, SINGLE-BLIND CLINICAL TRIAL TO ASSESS IMMUNOGENICITY IN ADULTS AGED 65 AND OVER
This study looks at giving COVID-19 and flu vaccines at the same time to people aged 65 and over. We want to see how well their bodies respond to both vaccines and if it's safe to have them together. This could make it easier for older adults to stay protected.
For: COVID-19 and fluBelgium · Netherlands - AuthorisedTherapeutic exploratory (Phase II)
Reduction of SystemiC Inflammation after ischemic stroke by intravenous DNase administration (ReSCInD)
This study looks at whether a drug called DNase can help reduce swelling and damage in the brain after a stroke. Researchers are testing if it lowers a chemical called IL-1β in the blood, which is linked to inflammation.
For: Reduction of SystemiC Inflammation after ischemic stroke by intravenous DNase administrationGermany - AuthorisedTherapeutic confirmatory (Phase III)
BALLAD Belgium - A trial to evaluate the potential benefit of adjuvant chemotherapy for small bowel adenocarcinoma. The Belgian component of the Global Ballad pooled data analysis.
This study, called BALLAD, is looking into whether extra chemotherapy after surgery can help people with a type of bowel cancer called small bowel adenocarcinoma. It's a big study involving different countries, and explores how long people live without the cancer coming back, and other important health measures.
For: small bowel adenocarcinomaBelgium - AuthorisedTherapeutic confirmatory (Phase III)
ANTIBIOBONTA - Assessment of the interest of a peri-operative antibiotic strategy applied to patients with asymptomatic bacteriuria undergoing intra-vesical botulinum toxin A injections
This study looks at whether antibiotics before and after bladder botulinum toxin A injections can prevent urine infections. It's for adults with bladder problems from multiple sclerosis or spinal cord injury, who also have bacteria in their urine without symptoms.
For: Patients (male or female) ≥18 years old with Detrusor overactivity (DO) in multiple sclerosis (MS) or spinal cord injured (SCI).France