- AuthorisedTherapeutic exploratory (Phase II)
A phase II efficacy and safety study of cell-free circulating tumor DNA-guided commencement of second-line treatment in patients with DLBCL/HGBCL relapse
This study looks at new ways to decide when to start a second treatment for certain types of lymphoma, using a blood test. It aims to see if this approach is safe and effective in helping patients.
For: Diffuse large B-cell lymphomas (DLBCL · Diffuse large B-cell lymphoma) and aggressive B-cell lymphomas (HGBCL · High-grade B-cell lymphoma) originate from mature B-cells at various stages of terminal differentiationPoland - Ongoing, recruitingPhase I and Phase II (Integrated)- Other
Phase 1/2 Study of Liposomal Annamycin in Combination with Cytarabine for the Treatment of Subjects with Acute Myeloid Leukemia (AML).
This study is looking at a new combination treatment for acute myeloid leukemia (AML), a type of blood cancer. It combines a new drug, Liposomal Annamycin, with a standard treatment, cytarabine. Researchers want to see if this new combination is safe and effective.
For: Acute Myeloid LeukemiaPoland · Italy - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Randomized, Double-Blind, Placebo-Controlled Multicenter Study of Levosimendan Therapy in low ejection fraction Takotsubo Syndrome (LevoTako Trial)
The LevoTako trial looks at a medicine called Levosimendan for people with a temporary heart condition called Takotsubo Syndrome. It's a large study to see if this medicine helps the heart recover faster while in the hospital.
For: Takotsubo syndromePoland - Ongoing, recruitingTherapeutic confirmatory (Phase III)
Evaluation of the efficacy of topical treatment with budesonide in children with Crohn's disease located in the esophagus and/or stomach and/or duodenum - BETHESDa
This study, called BETHESDa, is looking into how well a medicine called budesonide works for children with Crohn's disease that affects their food pipe, stomach, or the first part of their small bowel. They're checking if it can make visible signs of the disease disappear.
For: Crohn's diseasePoland - AuthorisedTherapeutic confirmatory (Phase III)
Impact of low dose epinephrine in the management of out-of-hospital cardiac arrest on neurological outcome: A multicenter randomized and double-blind trial (Low-EPI Study)
This study, called Low-EPI, is looking at whether a lower dose of adrenaline (epinephrine) given to people who have a sudden cardiac arrest outside of a hospital can help them recover better, especially with their brain function, compared to the usual dose. We want to see if it improves their health after 28 days.
For: Out-of-hospital cardiac arrest.France