- CompletedPhase III
A randomized trial of armpit (axilla) treatment for women with early stage breast cancer. POSNOC - POsitive Sentinel NOde: adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy.
The POSNOC trial looks at the best way to treat the armpit in women with early breast cancer. If cancer is found in one or two armpit glands, researchers want to see if standard drug therapies alone work just as well as having extra armpit surgery or radiotherapy.
For: Breast cancerUnited Kingdom · England · Australia - Active not recruitingPHASE3
Phase III Trial of Anaplastic Glioma Without 1p/19q Loss of Heterozygosity (LOH)
This study looks at treating a type of brain tumour called anaplastic glioma. It compares standard radiation treatment with adding a drug called temozolomide. Researchers want to see if adding temozolomide during or after radiation helps people live longer and improves their quality of life.
For: Brain and Central Nervous System TumorsUnited States · Australia · Belgium - Active not recruitingNA
POSNOC - A Trial Looking at Axillary Treatment in Early Breast Cancer
This study, called POSNOC, looks at whether women with early breast cancer and a small number of affected lymph nodes can skip extra armpit surgery or radiotherapy, and just have standard drug treatment. We want to see if this is just as effective.
For: Breast CancerAustralia · New Zealand · United Kingdom - Active not recruiting
Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy
This study looks at how young children with a type of brain tumour called ependymoma respond to standard chemotherapy. It also checks for long-term side effects to help doctors improve treatment for them in the future.
For: Brain and Central Nervous System Tumors · Cognitive/Functional Effects · Long-term Effects Secondary to Cancer Therapy in ChildrenUnited Kingdom