adsorbed) clinical trials

Proof of concept study to assess the efficacy and safety of Danicopan (factor D inhibitor) in adult patients with chronic spontaneous urticaria resistant to H1-antihistamine treatment (DANICSU).

This study looks at a new medicine called Danicopan for adults with long-lasting hives (urticaria) that haven't gotten better with standard allergy pills. It aims to see if Danicopan is safe and helps reduce hives, especially for those with different allergy levels.

CONDYVAC. Efficacy study of the quadrivalent Human Papilloma Virus (HPV) vaccine to prevent recurrence of External Genital Warts (EGW) in patients who were cured in the first place

This study looks at whether the HPV vaccine, Gardasil, can stop genital warts from coming back in people who have been successfully treated for them. It aims to see if the vaccine helps people stay wart-free after treatment.

Immune response to intradermally administered Ixiaro in healthy adults

This study looks at how well a Japanese encephalitis vaccine works when given into the skin, compared to a muscle. It checks the body's immune response and any side effects in healthy adults aged 18 to 64.

Prospective longitudinal study on immunogenicity, induction of cellular immune responses and safety of vaccination against HPV with the 9valent vaccine in HIV-positive women The Papillon study

This study looks at how well a vaccine called Gardasil 9 works for women with HIV. It checks if the vaccine helps their bodies fight against HPV, a common virus that can cause certain cancers. Researchers want to see if it's safe and effective for this group.

A Phase 3b, open-label, multi-center study to assess the immune response and safety of the meningococcal group B vaccine rMenB+OMV NZ when administered to healthy participants aged 10 to 20 years old, who were primed during the first 2 years of life

This study is looking at how well a meningitis B vaccine, Bexsero, works and how safe it is in young people aged 10-20. Participants would have had their first meningitis B vaccinations as babies. We want to see if a booster dose helps protect them.

COPD-2VAX: Enhancing Protection Against Respiratory Infections Through AS01-Mediated Innate Immune Activation in High-Risk Patients

This study looks at how new vaccines for lung conditions and common infections work in people with COPD. It aims to see if these vaccines can help their body's defenses (immune system) fight off respiratory illnesses better.

Multicenter, randomized, double-blinded, placebo-controlled phase 3 trial to evaluate nonavalent HPV vaccine as a secondary prevention in patients treated for human papilloma virus related high-grade squamous intraepithelial lesions.(BioHPV)

This study looks at whether a special HPV vaccine can stop abnormal cell changes from coming back after treatment. It's for people aged 18 and over who have had these changes, sometimes called HSIL, in areas like the cervix, vulva, or anus. The vaccine being tested is Gardasil 9.

A Phase 1b/2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Investigate A) the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses of IM-101 in Adult Participants with Generalized Myasthenia Gravis, and B) the Efficacy and Safety of Treatment of IM-101 in Adult Participants with Generalized Myasthenia Gravis and Ocular Myasthenia Gravis

This study is testing a new medicine, IM-101, for adults with Myasthenia Gravis (MG). It's looking at how safe it is and how well it works to improve symptoms of generalized and ocular MG.

A Phase III, open-label, randomized, controlled, multi-country study to evaluate the immune response, safety and reactogenicity of RSVPreF3 OA investigational vaccine when co-administered with 20-valent pneumococcal conjugate vaccine (PCV20) in adults aged 60 years and older.

A Phase II, Randomized, Partially Blinded Study to Assess the Safety, Tolerability and Immunogenicity of Meningococcal Combined ABCWY Vaccine when Administered to Healthy Infants

Phase III, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy of pre-surgical HPV9-valente vaccination in women treated with loop electrosurgical excision (LEEP) for high-grade cervical intraepithelial neoplasia (CIN2+) up to cervical cancer initially invasive (FIGO IA1) - HOPE 9 STUDY