- Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Multi-center, Randomized, Double-blind Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy
This study is testing a new medicine, Aficamten, for people with a heart condition called obstructive hypertrophic cardiomyopathy. It compares Aficamten to a common medicine, Metoprolol, to see if it helps patients feel better and improve how well their heart works. Researchers want to know if it's safe and effective.
For: Symptomatic Obstructive Hypertrophic CardiomyopathyDenmark · Italy · Hungary - Active not recruitingPHASE3
Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM
This study looks at a new medicine called aficamten for non-obstructive hypertrophic cardiomyopathy (nHCM). It compares aficamten to a dummy medicine (placebo) to see if it improves quality of life, exercise ability, and overall health in adults with nHCM.
For: Symptomatic Non-Obstructive Hypertrophic CardiomyopathyUnited States · Argentina · Australia - RecruitingPHASE2, PHASE3
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
This study is looking into a new medicine called Aficamten for young people aged 12-17 with a heart condition called hypertrophic cardiomyopathy (oHCM). It aims to see if the medicine is safe and effective in improving their symptoms, compared to a dummy medicine.
For: Pediatric · Symptomatic Obstructive Hypertrophic CardiomyopathyUnited States · Canada · Italy - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Multi-Center, Randomized, Double-Blind Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults with Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy
This study is testing a new tablet, Aficamten, for people with a heart condition called non-obstructive hypertrophic cardiomyopathy. It compares Aficamten to a dummy pill to see if it improves how people feel and their exercise ability.
For: SYMPTOMATIC NON-OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHYPoland · Spain · Italy