- AuthorisedTherapeutic use (Phase IV)
Comparing short to standard amoxicillin course for eRysipElas: a non-inferiority randomized controlled trial .SHARE II
This study looks at whether a shorter course of amoxicillin works as well as the usual course for a skin infection called erysipelas in adults. We want to see if patients get better just as quickly with less medicine.
For: Adults diagnosed with lower limbs erysipelasFrance - Ongoing, recruitingTherapeutic use (Phase IV)
Balloon + Oxytocin versus Oral Misoprostol to Induce labor in case of premature rupture of membranes (PROM) at term in nulliparous
This study compares two ways to help overdue mums-to-be whose waters have broken (premature rupture of membranes) have their baby. We're looking at whether a balloon or a tablet works best to start labour and how women feel about the process.
For: pregnant women with premature rupture of membranesFrance - Ongoing, recruitingTherapeutic confirmatory (Phase III)
COTRIVAP - Efficacy of cotrimoxazole as a de-escalation treatment of Ventilator-Associated Pneumonia in intensive care unit. Multicentric non-inferiority randomised controlled trial
This study is looking at whether a common antibiotic, co-trimoxazole, can be used to treat pneumonia in patients on a ventilator in intensive care. It compares it to standard treatments to see if it works just as well and is safe.
For: Intensive Care · Ventilator-associated PneumoniaFrance - AuthorisedTherapeutic use (Phase IV)
AIR. ANTIBIOTIC THERAPY IN RESPIRATORY TRACT INFECTIONS A controlled randomized, open label, multicenter, non-inferiority trial evaluating an individualized antibiotic treatment duration based on patient clinical response, evaluated through connected devices, for suspected community acquired pneumonia in the community setting
This study, called AIR, is looking at the best way to use antibiotics for chest infections (pneumonia). It compares different lengths of antibiotic treatment to see which works best, aiming to reduce how many antibiotics patients need.
For: Community acquired pneumonia (CAP)France - AuthorisedTherapeutic use (Phase IV)
Defining Antibiotic Levels in Intensive care patients (DALI-2) protocol - A multi-national pharmacokinetic/pharmacodynamic cohort study to determine whether contemporary antibiotic dosing for critically ill patients achieves therapeutic exposures.
This study looks at how well antibiotics work in very sick patients. Researchers want to make sure these important medicines reach the right levels in the body to fight serious infections effectively and safely. It's about getting the dose just right.
For: Serious infections in critically ill patients treated with antibioticsFrance