Treatment

AMOXICILLIN AND BETA-LACTAMASE INHIBITOR clinical trials

3 indexed studies · 0 currently recruiting

AuthorisedTherapeutic use (Phase IV)
AIR. ANTIBIOTIC THERAPY IN RESPIRATORY TRACT INFECTIONS A controlled randomized, open label, multicenter, non-inferiority trial evaluating an individualized antibiotic treatment duration based on patient clinical response, evaluated through connected devices, for suspected community acquired pneumonia in the community setting
This study, called AIR, is looking at the best way to use antibiotics for chest infections (pneumonia). It compares different lengths of antibiotic treatment to see which works best, aiming to reduce how many antibiotics patients need.
For: Community acquired pneumonia (CAP)
France
AuthorisedTherapeutic confirmatory (Phase III)
Efficacy of an empirical treatment with Amoxicillin-clavulanate (AC) compared to the combination Amoxicillin-clavulanate and Ciprofloxacin (AC+C) in the outpatient care of chemotherapy-induced fever in adult haematology patients. AC-CIF Protocol
This study looks at how well different antibiotic treatments work for adult cancer patients on chemotherapy who develop a fever. It compares two common antibiotic combinations to see which is better at getting rid of the fever without needing changes to treatment.
For: Adult patients treated for haematological disorders · in whom chemotherapy regimens are expected to induce neutropenia lasting <7 days
France
AuthorisedTherapeutic use (Phase IV)
Defining Antibiotic Levels in Intensive care patients (DALI-2) protocol - A multi-national pharmacokinetic/pharmacodynamic cohort study to determine whether contemporary antibiotic dosing for critically ill patients achieves therapeutic exposures.
This study looks at how well antibiotics work in very sick patients. Researchers want to make sure these important medicines reach the right levels in the body to fight serious infections effectively and safely. It's about getting the dose just right.
For: Serious infections in critically ill patients treated with antibiotics
France

Efficacy of an empirical treatment with Amoxicillin-clavulanate (AC) compared to the combination Amoxicillin-clavulanate and Ciprofloxacin (AC+C) in the outpatient care of chemotherapy-induced fever in adult haematology patients. AC-CIF Protocol

Defining Antibiotic Levels in Intensive care patients (DALI-2) protocol - A multi-national pharmacokinetic/pharmacodynamic cohort study to determine whether contemporary antibiotic dosing for critically ill patients achieves therapeutic exposures.