- Active not recruitingPHASE1
A Study Evaluating Anvumetostat in Combination With Other Therapies in Participants With Advanced Gastrointestinal, Biliary Tract, or Pancreatic Cancers With Homozygous Methylthioadenosine Phosphorylase (MTAP)-Deletion (MTAPESTRY 103)
This study looks at new drug combinations for treating advanced stomach, bile duct, and pancreatic cancers. It focuses on cancers with a specific genetic change (MTAP-deletion) to see how safe and effective these new treatments are.
For: Advanced Gastrointestinal, Biliary Tract, and Pancreatic CancersUnited States · Australia · Belgium - Active not recruitingPHASE1, PHASE2
A Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101)
This study is testing a new medicine, Anvumetostat, for people with advanced cancers that are missing a specific gene called MTAP. Researchers want to find the safest dose, see how well it works, and understand its side effects, sometimes given with another cancer drug called Docetaxel.
For: Advanced MTAP-null Solid TumorsUnited States · Australia · Austria