- AuthorisedTherapeutic confirmatory (Phase III)
Randomized double blind controlled trial comparing the safety and efficacy of apremilast versus placebo in severe forms of recurrent aphthous stomatitis - PREMS - 2019/0411/HP
This study is testing a new medicine called apremilast for people with severe mouth ulcers that keep coming back. We want to see if it helps heal the ulcers and stops them from returning, compared to a dummy pill. A key goal is to find out if taking apremilast leads to lasting relief.
For: Patients with severe forms of Recurrent Aphthous Stomatitis (RAS)France - RecruitingPHASE3
Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
This study, called REMAP-CAP, looks at different treatments for serious lung infections like pneumonia, flu, and COVID-19 in adults needing intensive care. It aims to find out which treatments work best to help patients recover.
For: Community-acquired Pneumonia, Influenza, COVID-19United States · Australia · Belgium - RecruitingPHASE3
Apremilast Pediatric Study in Children With Active Juvenile Psoriatic Arthritis
This study is looking into a medicine called apremilast for children and young people aged 5 to 17 who have a type of arthritis called juvenile psoriatic arthritis. It aims to see if this medicine works better than a dummy pill to reduce their arthritis symptoms.
For: Active Juvenile Psoriatic ArthritisAustria · Belgium · France - Active not recruitingPHASE3
A Study to Determine the Efficacy and Safety of Deucravacitinib Compared With Placebo in Participants With Active Psoriatic Arthritis (PsA) Who Are Naïve to Biologic Disease Modifying Anti-rheumatic Drugs or Had Previously Received TNFα Inhibitor Treatment
This study is testing a new medication called deucravacitinib for active psoriatic arthritis. It compares the new drug to a dummy pill to see if it helps people feel better and if it's safe. It's for people new to certain treatments or who have tried one specific type before.
For: Psoriatic ArthritisUnited States · Argentina · Australia - RecruitingPHASE3
Apremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet's Disease
This study is looking into a medicine called apremilast for children aged 2-17 with Behçet's disease who get recurring mouth ulcers. It aims to see if apremilast can help reduce these ulcers compared to a dummy medicine.
For: Behçet DiseaseFrance · Greece · Israel